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Donegan, Sarah; Welton, Nicky J.; Tudur Smith, Catrin; D'Alessandro, Umberto; Dias, Sofia – Research Synthesis Methods, 2017
Background: Many reviews aim to compare numerous treatments and report results stratified by subgroups (eg, by disease severity). In such cases, a network meta-analysis model including treatment by covariate interactions can estimate the relative effects of all treatment pairings for each subgroup of patients. Two key assumptions underlie such…
Descriptors: Network Analysis, Meta Analysis, Outcomes of Treatment, Comparative Analysis