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Direct linkShy, Michael E.; Jani, Agnes; Krajewski, Karen; Grandis, Marina; Lewis, Richard A.; Shy, Rosemary R.; Balsamo, Janne; Lilien, Jack; Garbern, James Y.; Kamholz, John – Brain, 2004
Myelin protein zero (MPZ) is a member of the immunoglobulin gene superfamily with single extracellular, transmembrane and cytoplasmic domains. Homotypic interactions between extracellular domains of MPZ adhere adjacent myelin wraps to each other. MPZ is also necessary for myelin compaction since mice which lack MPZ develop severe dysmyelinating…
Descriptors: Neurological Impairments, Genetics, Brain, Patients
