Objective: The purpose of this study was to investigate the association between sugar and NNS consumption with body fat percentage in young adults. Methods: 524 college students were asked to complete the Web-based National Institutes of Health (NIH) Diet History Questionnaire II and had their body fat percentage measured using a bioelectrical impedance analysis scale. Result: One-fourth of the participants were classified as overfat/obese and of those overfat or obese, 49% of them were African American. Overfat/obese participants consumed significantly more sugar than the heathy group and the underfat group (p<0.001). Saccharin consumption was significantly higher in the overfat/obese group compare to the underfat and normal groups (p<0.001). The odds of becoming overfat/obese increased 1.2 times for excessive total sugar consumption (95% CI: 1.0-1.8, p<0.05). Conclusion: Excessive sugar and saccharin consumption were associated with higher body fat percentage in young adults.