ERIC Number: EJ1306499
Record Type: Journal
Publication Date: 2021-Sep
Pages: 9
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0162-3257
EISSN: N/A
Brief Report: Associations between Self-Injurious Behaviors and Abdominal Pain among Individuals with ASD-Associated Disruptive Mutations
Kurtz-Nelson, Evangeline C.; Tham, See Wan; Ahlers, Kaitlyn; Cho, Daniel; Wallace, Arianne S.; Eichler, Evan E.; Bernier, Raphael A.; Earl, Rachel K.
Journal of Autism and Developmental Disorders, v51 n9 p3365-3373 Sep 2021
Self-injurious behaviors (SIB) are elevated in autism spectrum disorder (ASD) and related genetic disorders, but the genetic and biological mechanisms that contribute to SIB in ASD are poorly understood. This study examined rates and predictors of SIB in 112 individuals with disruptive mutations to ASD-risk genes. Current SIB were reported in 30% of participants and associated with poorer cognitive and adaptive skills. History of severe abdominal pain predicted higher rates of SIB and SIB severity after controlling for age and adaptive behavior; individuals with a history of severe abdominal pain were eight times more likely to exhibit SIB than those with no history. Future research is needed to examine associations between genetic risk, pain, and SIB in this population.
Descriptors: Self Destructive Behavior, Injuries, Autism, Pervasive Developmental Disorders, Genetic Disorders, Incidence, Predictor Variables, Behavior Problems, Pain, Severity (of Disability), Age Differences, Correlation
Springer. Available from: Springer Nature. One New York Plaza, Suite 4600, New York, NY 10004. Tel: 800-777-4643; Tel: 212-460-1500; Fax: 212-460-1700; e-mail: customerservice@springernature.com; Web site: https://bibliotheek.ehb.be:2123/
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: National Institute of Mental Health (NIMH) (DHHS/NIH); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (DHHS/NIH)
Authoring Institution: N/A
Grant or Contract Numbers: MH100047; MH101221; K23DK118111