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Direct linkBrianna Piro-Gambetti; Emily K. Schworer; Benjamin Handen; Masha Glukhovskaya; Sigan L. Hartley – Journal of Intellectual Disabilities, 2024
Adults with Down syndrome (DS) experience high risk for Alzheimer's disease (AD), but there is variability in the timing of transition from a cognitively stable state to prodromal AD and dementia. The present study examined the association between a modifiable lifestyle factor, employment complexity, and cognitive decline across two time points in…
Descriptors: Employment, At Risk Persons, Alzheimers Disease, Vocational Education
Leal, Stephanie L.; Ferguson, Lorena A.; Harrison, Theresa M.; Jagust, William J. – Learning & Memory, 2019
Most tasks test memory within the same day, however, most forgetting occurs after 24 h. Further, testing memory for simple words or objects does not mimic real-world memory experiences. We designed a memory task showing participants video clips of everyday kinds of experiences, including positive, negative, and neutral stimuli, and tested memory…
Descriptors: Memory, Alzheimers Disease, Stimuli, Recognition (Psychology)
Pistono, Aurélie; Jucla, M.; Bézy, C.; Lemesle, B.; Le Men, J.; Pariente, J. – International Journal of Language & Communication Disorders, 2019
Background: Alzheimer's disease is characterized by macrolinguistic changes. This decline is often analyzed with quantitative scales. Aims: To analyze discourse production in early Alzheimer's disease (AD) and to identify qualitative markers of macrolinguistic decline. Methods & Procedures: We analyzed macrolinguistic features of a clinical…
Descriptors: Alzheimers Disease, Correlation, Discourse Analysis, Identification
El Haj, Mohamad; Postal, Virginie; Allain, Philippe – Educational Gerontology, 2012
Studies have shown that the "Four Seasons" music may enhance the autobiographical performance of Alzheimer's disease (AD) patients. We used a repeated measures design in which autobiographical recall of 12 mild AD patients was assessed using a free narrative method under three conditions: (a) in "Silence," (b) after being exposed to the opus "Four…
Descriptors: Music, Alzheimers Disease, Diseases, Patients
Parker, Beth A.; Thompson, Paul D.; Jordan, Kathryn C.; Grimaldi, Adam S.; Assaf, Michal; Jagannathan, Kanchana; Pearlson, Godfrey D. – Research Quarterly for Exercise and Sport, 2011
The hippocampus is the primary site of memory and learning in the brain. Both normal aging and various disease pathologies (e.g., alcoholism, schizophrenia, and major depressive disorder) are associated with lower hippocampal volumes in humans and hippocampal atrophy predicts progression of Alzheimers disease. In animals, there is convincing…
Descriptors: Evidence, Exercise, Schizophrenia, Alzheimers Disease
Chang, Yu-Ling; Bondi, Mark W.; Fennema-Notestine, Christine; McEvoy, Linda K.; Hagler, Donald J., Jr.; Jacobson, Mark W.; Dale, Anders M. – Neuropsychologia, 2010
Understanding the underlying qualitative features of memory deficits in mild cognitive impairment (MCI) can provide critical information for early detection of Alzheimer's disease (AD). This study sought to investigate the utility of both learning and retention measures in (a) the diagnosis of MCI, (b) predicting progression to AD, and (c)…
Descriptors: Control Groups, Alzheimers Disease, Correlation, Verbal Learning
Colombo, Lucia; Fonti, Cristina; Stracciari, Andrea – Neuropsychologia, 2009
A group of 20 patients with probable Alzheimer disease (AD) and a control group were tested in a verb generation task, in a verb synonym task and several cognitive tests. Three types of verbs and novel verbs were presented in simple sentence frames, in two different conditions. In one condition participants were presented with the verb in the…
Descriptors: Control Groups, Semantics, Verbs, Alzheimers Disease
DenBesten, Nicholas P. – ProQuest LLC, 2009
This research involves an examination of the relationship between education and age on a wide array of neuropsychological test measures among patients diagnosed with Alzheimer's and vascular dementia. The purpose of this study was to investigate the role of education as an attenuating factor to neurocognitive decline in dementia. Although numerous…
Descriptors: Educational Attainment, Role of Education, Patients, Program Effectiveness
Hellweg, Rainer; Huber, Roman; Kuhl, Alexander; Riepe, Matthias W.; Lohmann, Peter – Learning & Memory, 2006
Impairment of hippocampal function precedes frontal and parietal cortex impairment in human Alzheimer's disease(AD). Neurotrophins are critical for behavioral performance and neuronal survival in AD. We used complex and radial mazes to assess spatial orientation and learning in wild-type and B6-Tg(ThylAPP)23Sdz (APP23) animals, a transgenic mouse…
Descriptors: Neurological Impairments, Nonverbal Learning, Correlation, Memory
Hodgson, Lynne Gershenson; Cutler, Stephen J. – International Journal of Aging and Human Development, 2003
This study examined the correlates of symptom-seeking behavior for Alzheimer's disease (AD) among middle-aged persons. Symptom seeking, the tendency to search for signs of disease, is one manifestation of an individual's concern about developing AD. The data were obtained from a survey of two subsamples of 40-60 year old adults: 1) 108 adult…
Descriptors: Memory, Alzheimers Disease, Symptoms (Individual Disorders), Correlation
Burton, Catherine; Crossley, Margaret – Canadian Journal on Aging, 2003
The Saskatchewan Mood Inventory (SMI) is a caregiver-focused assessment and research tool that was designed to enhance understanding of the emotional experiences of individuals with dementia and to identify relationships between level of cognitive impairment and family member ratings of pleasant and unpleasant emotional responses during daily…
Descriptors: Emotional Response, Dementia, Foreign Countries, Psychological Patterns
Tiernan, Kristine N.; Schenk, Kelli; Swadberg, Danielle; Shimonova, Marianna; Schollaert, Daniel; Boorkman, Patti; Cherrier, Monique M. – Clinical Psychologist, 2004
The validity and reliability of a novel route learning test were examined to assess the effectiveness of its use in evaluating spatial memory in healthy older adults and patients with Alzheimer's disease (AD). The Puget Sound Route Learning Test was significantly correlated with an existing measure of cognitive ability, the Dementia Rating Scale.…
Descriptors: Alzheimers Disease, Dementia, Test Validity, Rating Scales
Sano, Mary; Aisen, Paul S.; Dalton, Arthur J.; Andrews, Howard F.; Tsai, Wei-Yann – Journal of Policy and Practice in Intellectual Disabilities, 2005
A major challenge to developing therapeutic interventions for cognitive loss and dementia in aging individuals with Down syndrome (DS) is the selection of appropriate outcome measures. This report describes the adaptation of the Brief Praxis Test (a nonverbal cognitive test) as a primary outcome measure, as well as the selection of secondary…
Descriptors: Mental Retardation, Alzheimers Disease, Dementia, Down Syndrome
