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Pakhomov, Serguei V. S.; Hemmy, Laura S.; Lim, Kelvin O. – Neuropsychologia, 2012
The objective of our study is to introduce a fully automated, computational linguistic technique to quantify semantic relations between words generated on a standard semantic verbal fluency test and to determine its cognitive and clinical correlates. Cognitive differences between patients with Alzheimer's disease and mild cognitive impairment are…
Descriptors: Semantics, Alzheimers Disease, Diseases, Patients
Possin, Katherine L.; Laluz, Victor R.; Alcantar, Oscar Z.; Miller, Bruce L.; Kramer, Joel H. – Neuropsychologia, 2011
Figure copy is the most common method of visual spatial assessment in dementia evaluations, but performance on this test may be multifactorial. We examined the neuroanatomical substrates of figure copy performance in 46 patients with Alzheimer's disease (AD) and 48 patients with the behavioral variant of Frontotemporal dementia (bvFTD). A group of…
Descriptors: Alzheimers Disease, Neurology, Short Term Memory, Brain
Voss, Michelle W.; Erickson, Kirk I.; Prakash, Ruchika S.; Chaddock, Laura; Malkowski, Edward; Alves, Heloisa; Kim, Jennifer S.; Morris, Katherine S.; White, Siobhan M.; Wojcicki, Thomas R.; Hu, Liang; Szabo, Amanda; Klamm, Emily; McAuley, Edward; Kramer, Arthur F. – Neuropsychologia, 2010
Over the next 20 years the number of Americans diagnosed with dementia is expected to more than double (CDC, 2007). It is, therefore, an important public health initiative to understand what factors contribute to the longevity of a healthy mind. Both default mode network (DMN) function and increased aerobic fitness have been associated with better…
Descriptors: Alzheimers Disease, Public Health, Physical Fitness, Diseases
Cuetos, Fernando; Herrera, Elena; Ellis, Andrew W. – Neuropsychologia, 2010
Studies of word production in patients with Alzheimer's disease have identified the age of acquisition of words as an important predictor of retention or loss, with early acquired words remaining accessible for longer than later acquired words. If, as proposed by current theories, effects of age of acquisition reflect the involvement of semantic…
Descriptors: Semantics, Alzheimers Disease, Patients, Word Recognition
Chang, Yu-Ling; Bondi, Mark W.; Fennema-Notestine, Christine; McEvoy, Linda K.; Hagler, Donald J., Jr.; Jacobson, Mark W.; Dale, Anders M. – Neuropsychologia, 2010
Understanding the underlying qualitative features of memory deficits in mild cognitive impairment (MCI) can provide critical information for early detection of Alzheimer's disease (AD). This study sought to investigate the utility of both learning and retention measures in (a) the diagnosis of MCI, (b) predicting progression to AD, and (c)…
Descriptors: Control Groups, Alzheimers Disease, Correlation, Verbal Learning
Colombo, Lucia; Fonti, Cristina; Stracciari, Andrea – Neuropsychologia, 2009
A group of 20 patients with probable Alzheimer disease (AD) and a control group were tested in a verb generation task, in a verb synonym task and several cognitive tests. Three types of verbs and novel verbs were presented in simple sentence frames, in two different conditions. In one condition participants were presented with the verb in the…
Descriptors: Control Groups, Semantics, Verbs, Alzheimers Disease