The purpose of Title I, Part A of the Elementary and Secondary Education Act (ESEA; 20 U.S.C. § 6301 et seq.) is to provide all children with a fair, equitable, and high-quality education, and to close educational achievement gaps. Title I, Part A is designed to meet the educational needs of low-achieving children in schools with the highest levels of poverty by aligning high-quality assessments, systems of accountability, teacher preparation, curriculum, and instructional materials with challenging State academic standards. This brief explains how Title I, Part A of the ESEA, as amended by the Every Student Succeeds Act of 2015 (ESSA), and the McKinney-Vento Act, as amended by the ESSA, intersect, and offers strategies for effective cross-program collaboration. [For the first version of this brief "Serving Students Experiencing Homelessness under Title I, Part A. McKinney-Vento Law into Practice Brief Series," see ED574592.]