The purpose of this qualitative descriptive study was to investigate how leaders described their experiences with team collaboration, organizational knowledge creation, and organizational culture when using Artificial Intelligence in companies in the Western United States. Nonaka and Takeuchi's SECI Knowledge Spiral model was used to underpin this study. This study asked three research questions: how leaders described their experiences when managing teams that collaborated while using AI in companies, how did leaders describe their experiences when managing teams that created organizational knowledge while using AI in companies, and how did leaders describe their experiences when managing teams that sought a supportive organizational culture while using AI in companies. The researcher purposively selected 23 business leaders who use AI. Twenty-one semi-structured interviews, resulting in 188 single-spaced pages transcribed, and 22 questionnaires with 16 questions each served as this study's two data sources. Braun and Clarke's phased thematic analysis was used to analyze the data. The themes that emerged from the data were (a) AI is effective when being used for collaborating in organizations, (b) AI is an evolving set of collaboration tools that can help people to achieve better results, (c) AI is effective when being used for innovating in organizations, (d) business leaders should apply sound judgment when using AI to innovate, (e) business leaders need to be held accountable for decisions made when using AI to promote a healthy organizational culture, and (f) employees need to trust that using AI will benefit them to sustain a healthy organizational culture. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://bibliotheek.ehb.be:2222/en-US/products/dissertations/individuals.shtml.]