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Direct linkVieira, Philip A.; Lovelace, Jonathan W.; Corches, Alex; Rashid, Asim J.; Josselyn, Sheena A.; Korzus, Edward – Learning & Memory, 2014
The neural mechanisms underlying the attainment of fear memory accuracy for appropriate discriminative responses to aversive and nonaversive stimuli are unclear. Considerable evidence indicates that coactivator of transcription and histone acetyltransferase cAMP response element binding protein (CREB) binding protein (CBP) is critically required…
Descriptors: Neurological Organization, Neurology, Fear, Memory
Kushnir, Jonathan; Sadeh, Avi – Child Psychiatry and Human Development, 2010
The objective is to examine underlying associations between childhood fears, behavior problems and neurobehavioral functioning (NBF) in school-age children. Healthy, regular school children (N = 135), from second, fourth and sixth grade classes were assessed. Data regarding children's fears and behavioral problems were obtained with the Revised…
Descriptors: Check Lists, Behavior Problems, Child Behavior, Short Term Memory
Wiltgen, Brian J.; Sanders, Matthew J.; Ferguson, Carolyn; Homanics, Gregg E.; Fanselow, Michael S. – Learning & Memory, 2005
The [delta] subunit of the GABA[subscript [Alpha]] receptor (GABA[subscript [Alpha]]R) is highly expressed in the dentate gyrus of the hippocampus. Genetic deletion of this subunit reduces synaptic and extrasynaptic inhibition and decreases sensitivity to neurosteroids. This paper examines the effect of these changes on hippocampus-dependent trace…
Descriptors: Conditioning, Inhibition, Fear, Animals
