This annual report provides information regarding students who registered with disability services at Maryland colleges and universities. To better understand higher education outcomes for students with disabilities in Maryland, the Maryland Higher Education Commission (MHEC), in collaboration with the Maryland Department of Disabilities and in partnership with the state's higher education institutions, created a survey administered to colleges and universities to collect these data in aggregate form. The information may be used to improve policies and practices to support the success of students with disabilities. In fiscal year 2021, 15,937 undergraduate students and 2,024 graduate students were registered with their institutions' disability services office as students with disabilities, which represents 4.0% of all students enrolled in fiscal year 2021, almost no change from the previous year. Specifically, this represents 4.5% of undergraduate students and 2.2% of graduate students enrolled. [For the 2022 edition of this report, see ED618780.]