Metabolic Control Analysis (MCA) is a systems biology approach that measures the control of a metabolic step on the overall flux of a metabolic pathway. In undergraduate courses in biochemistry, learning of MCA can be encouraged by experimental activities demonstrating practical applications of the MCA theory. In this work, we present a laboratory…

Multistep synthesis is a key capstone experience in organic laboratory instruction. Here, a four-step synthesis of avobenzone, an active component in sunscreens, has been developed that can be completed in two 4 h laboratory periods. This synthesis incorporates green principles and includes an aldol condensation, electrophilic addition of bromine…

A multistep synthesis of a novel arylidene 3­(2"H")-furanone has been designed and optimized for the second-year organic laboratory. The three-step sequence consists of a nucleophilic substitution, intramolecular cyclization, and acid-catalyzed aldol condensation, and can be carried out within two 3 h laboratory periods. The final…

Organizing undergraduates in chemistry, energy engineering, and chemical engineering specialties to participate in an energy transformation experiment can encourage them to think about the impact of human activities on nature and stimulate them to learn more about the topic. This laboratory experiment demonstrates a general approach to the…

This experimental lab set is for students taking college chemistry courses. It includes four laboratory works and completely illustrates the important parts of chemical kinetics, namely the determination of the rate constant and the determination of the factors influencing its value. They can be used in a laboratory set for a physical chemistry…

We describe a guided-inquiry laboratory experiment for instrumental analysis in which our students test an improved protocol for the recycling of silver chloride to produce nontoxic waste. Students are provided with samples of silver chloride that they created as waste products in a previous lab experiment and tasked with performing a stepwise…

Nowadays, novel Biochemistry lab techniques are being introduced at a very fast pace in scientific research. This requires development of new labs for undergraduate Biochemistry courses to equip the students with up-to-date techniques. However, the time limit of Biochemistry labs for undergraduate students represents a major obstacle. This article…

Raman spectroscopy is an important vibrational spectroscopy tool to characterize chemical compounds. As only a few photons undergo Raman scattering, enhancement of signal is a vital requirement. In this laboratory experiment, some practical aspects of Raman spectroscopy and how a simple enhancement procedure can be used to detect a Raman signal…

The pendulum was an important scientific instrument in the 17th century. It became a typical textbook problem in the 18th century. After the introduction of vectors in physics in the 1890s, the pendulum problem started to be progressively solved in the manner we know nowadays from introductory mechanics courses. Starting from "F = ma"…

Heart muscle cells, or cardiomyocytes, exhibit intrinsic contractility in vitro. We found that commercially-available mammalian cardiomyocytes serve as an excellent model system for studying the cytoskeleton and cellular contractility, fundamental topics in undergraduate cell and molecular biology courses. Embryonic rat cardiomyocytes were plated…

We present the use of an oxygen tolerant controlled radical polymerization (photoinduced electron/energy transfer-reversible addition fragmentation chain transfer polymerization, PET-RAFT) as a simple method for preparing controlled radical polymers in an undergraduate laboratory. Unlike conventional techniques, PET-RAFT polymerizations require no…

Exciting developments in the field of Green Chemistry spur the continuous innovation of experiments in the teaching laboratory. Beyond learning practical techniques, students can critically assess experiments using relevant metrics to propose further improvements and identify the most important interconnected impacts of these alternative products…

Dendrite growth affects material systems across applications as diverse as lithium batteries, organic light emitting diodes, turbine blades, and biological sensors. Their unique crystal structure and ability to physically see growth make for a unique undergraduate laboratory experience. This experiment uses dendrite growth to explore the physical…

Carbohydrates are an essential group of molecules to the organic chemistry classroom providing molecular relevance to a common ingredient in chemical biology. While the meticulous elucidation of the carbohydrate structures by Fischer and others is an engaging topic in the lecture, there are few laboratory experiments that can emulate carbohydrate…

Williamson ether experiments are commonly performed by students in undergraduate organic chemistry instructional laboratory courses. In this multioutcome experiment, students were provided 4-bromophenol and one of three alkyl halides: 1-bromopentane, 1-bromobutane, or 1-bromo-3-methylbutane. The alkyl halides served as the unknown component of the…