The American Chemical Society advocates a shift from rule-based to risk-based safety education for chemistry graduates, emphasizing meaningful student engagement in the risk assessment process for laboratory work. To implement this paradigm shift, we introduced RAMP (Recognize Hazards, Assess Risk, Minimize Risk, and Prevent Emergencies)-based…

TNT is both toxic and explosive, and therefore, the detection of TNT represents an environmental concern and a security concern. Dogs are often used for detection, but other methods are needed. This laboratory investigates a ruthenium bipyridine ([Ru(bpy)[subscript 3]][superscript 2+]) luminescence-based trinitrotoluene (TNT) sensor. Students will…

Chemistry in water is an emerging field that fulfills the fifth principle of green chemistry: replacing toxic organic solvents with their benign counterparts. Although some pharmaceutical industries have developed and adopted chemistry in water, its implementation in teaching laboratories is still limited. Therefore, we have designed an experiment…

This paper describes the course outline for a three credit hour nonlaboratory course in Environmental Health Chemistry which was taught from 1981 until 2008 at the State University of New York College at Oneonta. The purpose of this paper is to share the lecture outline in the hopes that it might be useful to others who are preparing to teach…

Developing strong safety cultures in academic institutions requires that students at all levels be educated by faculty in chemical safety. Yet chemical safety education is missing from the chemistry curriculum. This article considers a report of numerous injuries from incidents from using flammable chemicals in demonstrations as evidence that…

We describe a series of three experiments in which students develop a model system for measuring the LC50 of household substances, using grass seed as the model organism. Students use statistical methods to compare two samples (using chi-square and Student's "t"-tests), conduct a two-level multifactor experiment to look at multiple…

RAMP is an acronym for the process "recognize hazards, assess risk, minimize risk, and prepare for emergencies". This paper describes these four steps in the context of undergraduate instruction about chemical health and safety.

This work presents a simple protocol that demonstrates the use of an inexpensive household carbon monoxide detector as a useful tool to detect the release of carbon monoxide gas from thermal cheletropic decarbonylation reactions. The carbon monoxide detection method described has been employed in a short series of reactions used in a university…

While lab accidents that involved personal injuries or significant property damage are required to be reported by law, many minor lab incidents or near misses are less frequently reported, especially in an academic research environment. However, public awareness of these stories and incidents create valuable learning opportunities and can prevent…

The variation in curricular approaches to and content of chemical safety instruction in undergraduate programs highlight the need for a more comprehensive, integrative approach. This work describes the efforts of two institutions, Wittenberg University and St. Olaf College, to develop and to implement a chemical safety curriculum across the…

Green chemistry metrics and life-cycle analysis (LCA) were used to assess inefficiencies in two current organic chemistry experiments conducted in third-year organic chemistry to synthesize ("E")-stilbene from benzaldehyde. An alternative Wittig-based, greener, one-pot experiment using the same starting material was selected as a vehicle…

This paper examines the current state of the implementation of green chemistry into organic chemistry textbooks. Content analysis of the 15 most used organic chemistry textbooks revealed that only 10 of them had any mention of green chemistry. In textbooks that contained mentions of green chemistry, it was mentioned on less than 1% of pages. Green…

A method to synthesize biaryls through the Suzuki-Miyaura cross-coupling reaction using a recyclable fluorous precatalyst is described. This laboratory experiment, which demonstrates the safety benefits of green chemistry, is integrated into an upper-division course. Besides simply using the catalyst for a reaction, students can reuse the catalyst…

At many universities, silver nitrate is used in teaching laboratories, and a resulting waste product is often silver chloride. Silver chloride is not a compound that can be discarded into a sink as it has harmful effects to the environment; however, commercial waste disposal is costly, and replacement of the silver nitrate reagent is expensive.…

Polychlorinated biphenyls (PCBs) are a family of synthetic chemicals consisting of carbon, hydrogen, and chlorine atoms. PCBs have been produced commercially since 1929 in hundreds of industrial applications. Their continued production in the United States was phased out in the late 1970s, and strict disposal guidelines were regulated as adverse…