Written by the SECEIJ Special Forum editorial team, this Project Report summarizes the interdisciplinary, collaborative, and inspiring research journey and theoretical background leading to the creation of a strategic plan for the 'IKE Alliance for Transforming STEM Education. 'IKE, which stands for Indigenous Knowledges, Encouragements, Engagements, and Experiences, means knowledge in the Native Hawaiian language. This article outlines the importance of honoring Indigenous epistemologies in STEM education and across institutions and communities as we work to increase the presence of Native American, Alaska Native, Native Hawaiian, and Pacific Islander students in STEM. Our goal is to build authentic and durable partnerships locally and nationally through respecting, honoring, engaging, cultivating, and consulting with Native Nations and communities.