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Jacobs, Heidi I. L.; Van Boxtel, Martin P. J.; Uylings, Harry B. M.; Gronenschild, Ed H. B. M.; Verhey, Frans R.; Jolles, Jelle – Brain and Cognition, 2011
Cortical grey matter atrophy patterns have been reported in healthy ageing and Alzheimer disease (AD), but less consistently in the parietal regions of the brain. We investigated cortical grey matter volume patterns in parietal areas. The grey matter of the somatosensory cortex, superior and inferior parietal lobule was measured in 75 older adults…
Descriptors: Group Membership, Alzheimers Disease, Brain Hemisphere Functions, Cognitive Processes
Sylvain-Roy, Stephanie; Bherer, Louis; Belleville, Sylvie – Brain and Cognition, 2010
Temporal preparation was assessed in 15 Alzheimer's disease (AD) patients, 20 persons with mild cognitive impairment (MCI) and 28 healthy older adults. Participants completed a simple reaction time task in which the preparatory interval duration varied randomly within two blocks (short versus long temporal window). Results indicated that AD and…
Descriptors: Intervals, Reaction Time, Alzheimers Disease, Brain
Mapstone, Mark; Dickerson, Kathryn; Duffy, Charles J. – Brain, 2008
Similar manifestations of functional decline in ageing and Alzheimer's disease obscure differences in the underlying cognitive mechanisms of impairment. We sought to examine the contributions of top-down attentional and bottom-up perceptual factors to visual self-movement processing in ageing and Alzheimer's disease. We administered a novel…
Descriptors: Alzheimers Disease, Aging (Individuals), Older Adults, Cognitive Ability
Margallo-Lana, M. L.; Moore, P. B.; Kay, D. W. K.; Perry, R. H.; Reid, B. E.; Berney, T. P.; Tyrer, S. P. – Journal of Intellectual Disability Research, 2007
Background: The clinical and neuropathological features associated with dementia in Down's syndrome (DS) are not well established. Aims: To examine clinico-pathological correlations and the incidence of cognitive decline in a cohort of adults with DS. Method: A total of 92 hospitalized persons with DS were followed up from 1985 to December 2000.…
Descriptors: Adjustment (to Environment), Adults, Patients, Incidence
Ball, S. L.; Holland, A. J.; Huppert, F. A.; Treppner, P.; Watson, P.; Hon, J. – Journal of Intellectual Disability Research, 2004
Dementia because of Alzheimer's disease (AD) commonly affects older adults with Down's syndrome (DS). Methods are needed, with established concurrent and predictive validity, to facilitate the diagnostic assessment of dementia, when it is complicated by pre-existing intellectual disabilities (ID). We report on the reliability and validity of a…
Descriptors: Identification, Predictive Validity, Interrater Reliability, Alzheimers Disease
Perkins, Elizabeth A.; Small, Brent J. – Journal of Policy and Practice in Intellectual Disabilities, 2006
Recently, more attention is being given to identifying aging-related and dementia-related pathological changes in performance and cognition among persons with intellectual disabilities (ID). This literature review examines age-related differences in specific aspects of cognitive functioning and cognitive performance of people with ID and…
Descriptors: Mental Retardation, Alzheimers Disease, Dementia, At Risk Persons

Williams, Barbara; Roberts, Pamela – International Journal of Aging & Human Development, 1995
Participant observation study explored social interactions and friendships among cognitively impaired adult day-care participants. Found clients engage in a variety of social interactions and friendships, enabling them to maintain a sense of self and to adjust to group norms. Discussed general socializing, enduring friendships, helping…
Descriptors: Adult Day Care, Alzheimers Disease, Case Studies, Cognitive Ability