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Kangas, Brian D.; Branch, Marc N. – Journal of the Experimental Analysis of Behavior, 2012
The effects of cocaine were examined under a titrating-delay matching-to-sample procedure. In this procedure, the delay between sample stimulus offset and comparison stimuli onset adjusts as a function of the subject's performance. Specifically, matches increase the delay and mismatches decrease the delay. Titrated delay values served as the…
Descriptors: Cocaine, Drug Abuse, Animals, Animal Behavior
Pinkston, Jonathan W.; Branch, Marc N. – Journal of the Experimental Analysis of Behavior, 2010
The present experiment examined the effects of acute and daily cocaine on spontaneous behavior patterns of pigeons. After determining the acute effects of a range of doses, 9 pigeons were divided into three groups that received one of three doses of cocaine daily, either 1.0, 3.0, or 10.0 mg/kg cocaine. Measures were taken of spontaneous…
Descriptors: Behavior Patterns, Cocaine, Persistence, Psychomotor Skills
Yoon, Jin Ho; Branch, Marc N. – Journal of the Experimental Analysis of Behavior, 2009
Under multiple schedules of reinforcement, previous research has generally observed tolerance to the rate-decreasing effects of cocaine that has been dependent on schedule-parameter size in the context of fixed-ratio (FR) schedules, but not under the context of fixed-interval (FI) schedules of reinforcement. The current experiment examined the…
Descriptors: Intervals, Food, Cocaine, Reinforcement
Weaver, Matthew T.; Branch, Marc N. – Journal of the Experimental Analysis of Behavior, 2008
Tolerance to effects of cocaine can be modulated by schedules of reinforcement. With multiple ratio schedules, research has shown an inverse relationship between ratio requirement and amount of tolerance that resulted from daily administration of the drug. In contrast, tolerance to the effects of cocaine on behavior under multiple interval…
Descriptors: Reinforcement, Cocaine, Intervals, Animals
Pinkston, Jonathan W.; Branch, Marc N. – Journal of the Experimental Analysis of Behavior, 2004
Daily administration of cocaine often results in the development of tolerance to its effects on responding maintained by fixed-ratio schedules. Such effects have been observed to be greater when the ratio value is small, whereas less or no tolerance has been observed at large ratio values. Similar schedule-parameter-dependent tolerance, however,…
Descriptors: Drug Use, Animals, Animal Behavior, Behavioral Science Research
Pinkston, Jonathan W.; Branch, Marc N. – Journal of the Experimental Analysis of Behavior, 2004
Effects of repeated administration of cocaine to animals behaving under operant contingencies have depended on when the drug is given. Moderate doses given presession have generally led to a decrease in the drug's effect, an outcome usually referred to as tolerance. When these same doses have been given after sessions, the usual result has been no…
Descriptors: Reinforcement, Classical Conditioning, Multivariate Analysis, Cocaine