Institutionalized patients with Down syndrome (N=307) were monitored for 5 to 10 years to determine prevalence of Alzheimer-type dementia. Prevalence increased from 11% between ages 40 and 49 to 77% between 60 and 69. All patients 70 and over had dementia. Mean age of onset of dementia was 56 years. Neuropathological findings were consistent with…

Notes that, as American population ages and mental health counselors focus services on older adults, the identification, diagnosis, assessment, and treatment of dementia will become valuable clinical skill. Presents nontechnical information regarding dementia, including Alzheimer's disease, multi-infarct dementia, testing, and therapeutic…

This report describes the status of 70 adults (ages 22 to 60 at the longitudinal study's beginning) with Down syndrome who are being followed for signs of dementia. After 10 years, 12 met all criteria for dementia, 40 met subsets of criteria, and 18 met no criteria. Information is provided on choice and revision of instruments and dementia…

Similar to the state of the broader intellectual disabilities field, many gaps exist in the research and treatment of mental health concerns in people with Down syndrome. This review summarizes key findings on the type and prevalence of behavior and emotional problems in children, adolescents, and adults with Down syndrome. Such findings include…

Describes the demographic features and clinical diagnoses in a sample of 58 demented urban black outpatients. Results indicate that probable Alzheimer's disease was the most common cause of dementia whereas probable vascular dementia was uncommon. A multiple etiology dementia was identified in more than one-third of the patients. (RJM)

Emotional factors were studied in 30 adults with Down's syndrome, 18 controls with Alzheimer disease, and 25 elderly controls without mental retardation. Primary emotional factors separating Down's syndrome and Alzheimer disease groups from elderly control subjects without mental retardation were indifference, pragnosia, and inappropriateness.…

In order to assess vision in Alzheimer's disease, gerontologists must use tests that make minimal cognitive demands on the subject. Using such tests revealed a pattern of deficits in color discrimination, stereoacuity, contrast sensitivity, and backward masking. Impaired vision predicts deficient performance on numerous tests of cognition. (JPS)

Thirty-eight elderly control subjects performed better than did 18 patients with moderate Alzheimer's disease (AD), 33 with severe AD, and 12 with Parkinson's dementia on all measures of the Rey Auditory Verbal Learning Test. Results indicate that the test is useful in distinguishing AD from Parkinson's dementia. (SLD)

Dementia because of Alzheimer's disease (AD) commonly affects older adults with Down's syndrome (DS). Methods are needed, with established concurrent and predictive validity, to facilitate the diagnostic assessment of dementia, when it is complicated by pre-existing intellectual disabilities (ID). We report on the reliability and validity of a…

Assessing higher cerebral functions in patients with known or suspected dementia requires sampling numerous abilities quickly and accurately. This paper reports on the performance of 20 patients with probable dementia of the Alzheimer's type (DAT) on the BNI Screen for Higher Cerebral Functions (BNI Screen). These patients' performances were…

The level of agreement between the patient and a collateral source with regard to depressive symptomatology was compared for 185 patients with Alzheimer's-type dementia (AD), 57 patients with Parkinson's disease, and 54 nondemented geriatric referrals. Findings highlight the potential insensitivity of patient report in AD. (SLD)

A study examined two methods of using the Vineland Adaptive Behavior Scales with people with Down syndrome at risk of developing Alzheimer's disease. Scoring the scales using the basal rule outlined in the manual resulted in highlighting significant declines in scores for those meeting the criteria for "probable Alzheimer's disease."…

This article raises critical issues that need to addressed while considering the future needs of people with Down syndrome and dementia, along with suggestions as to how they may be met. It discusses dementia diagnosis, staff training, the family's role, advantages of health screening, and difficulties in collating accurate information. (Contains…

Reviews causes of dementia in later life, especially the Alzheimer's type, its prevalence, the characteristic structural changes, and hypothesized causes. The hypothesis that Alzheimer's disease represents accelerated aging is described. Treatment issues are discussed, primarily in terms of supportive environments, differential diagnosis, and…

The validity and reliability of a novel route learning test were examined to assess the effectiveness of its use in evaluating spatial memory in healthy older adults and patients with Alzheimer's disease (AD). The Puget Sound Route Learning Test was significantly correlated with an existing measure of cognitive ability, the Dementia Rating Scale.…