Background: The detection and description of language impairments in neurodegenerative diseases like Alzheimer's Disease (AD) play an important role in research, clinical diagnosis and intervention. Various methodological protocols have been implemented for the assessment of morphosyntactic abilities in AD; narrative discourse elicitation tasks…

Early differential diagnosis of dementia is becoming increasingly important as new pharmacologic therapies are developed, as these treatments are not equally effective for all types of dementia. Early detection and differential diagnosis also facilitates informed family decision making and timely access to appropriate services. Information about…

Background: Apraxia is neurologically induced deficit in the ability perform purposeful skilled movements. One of the most common forms is ideomotor apraxia (IMA) where spatial and temporal production errors are most prevalent. IMA can be associated Alzheimer's disease (AD), even early in its course, but is often not identified possibly because…

This report describes the status of 70 adults (ages 22 to 60 at the longitudinal study's beginning) with Down syndrome who are being followed for signs of dementia. After 10 years, 12 met all criteria for dementia, 40 met subsets of criteria, and 18 met no criteria. Information is provided on choice and revision of instruments and dementia…

Assessing higher cerebral functions in patients with known or suspected dementia requires sampling numerous abilities quickly and accurately. This paper reports on the performance of 20 patients with probable dementia of the Alzheimer's type (DAT) on the BNI Screen for Higher Cerebral Functions (BNI Screen). These patients' performances were…

The level of agreement between the patient and a collateral source with regard to depressive symptomatology was compared for 185 patients with Alzheimer's-type dementia (AD), 57 patients with Parkinson's disease, and 54 nondemented geriatric referrals. Findings highlight the potential insensitivity of patient report in AD. (SLD)

A study examined two methods of using the Vineland Adaptive Behavior Scales with people with Down syndrome at risk of developing Alzheimer's disease. Scoring the scales using the basal rule outlined in the manual resulted in highlighting significant declines in scores for those meeting the criteria for "probable Alzheimer's disease."…