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Friede, Tim; Röver, Christian; Wandel, Simon; Neuenschwander, Beat – Research Synthesis Methods, 2017
Meta-analyses in orphan diseases and small populations generally face particular problems, including small numbers of studies, small study sizes and heterogeneity of results. However, the heterogeneity is difficult to estimate if only very few studies are included. Motivated by a systematic review in immunosuppression following liver…
Descriptors: Meta Analysis, Diseases, Medical Research, Research Problems