In elementary and secondary classrooms, educators use plants for various reasons. Plants are often used during learning activities and science experiments. Also, educators frequently decorate their classrooms with plants to make the room more inviting and comfortable. Few new educators have been informed of the potential hazards of commonly known plants that have toxic characteristics. Because of this lack of knowledge, children may be harmed by touching or ingesting parts of plants found in the classroom. This article presents ten plants often found in the classroom that have toxic characteristics. Plants that are non-toxic and can be safely substituted in the classroom are also described. (Contains 3 tables and 10 photos.)