A novel undergraduate analytical chemistry experiment involving the identification and quantification of linalool in essential oils was developed. The experiment uses the internal standard method with headspace solid phase microextraction (SPME) and gas chromatography--mass spectrometry (GC-MS). This method is applicable to any linalool-containing…

Zinc oxide is a common additive in food, cosmetics, and medicines. Here, we describe the validation of methods to analyze two pharmaceutical samples containing ZnO--talc powder and dermal ointment--by ethylenediaminetetraacetic acid (EDTA) titration. The methods developed were implemented as a practical class to students of a Quantitative Analysis…

A green chemistry experiment is presented for teaching an undergraduate quantitative analysis/analytical chemistry laboratory class through the use of black tea leaf extract for the determination of iron in supplement tablets. Dried tea leaf is a safe, low cost, and widely available source of natural extract that can be used in place of more toxic…

Here, we describe the implementation a hybrid general chemistry teaching laboratory curriculum that replaces a portion of a course's traditional "wet lab" experiences with online virtual lab modules. These modules intentionally utilize representations on all three levels of the chemistry triplet-macroscopic, submicroscopic, and symbolic.…

Quantification of the many constituents that make up our food, whether they are desirable (vitamins, antioxidants, nutrients) or undesirable (pesticides, toxins), is one of the most practical applications of chemistry. In this study, kombucha, a popular fermented tea beverage, was analyzed using acid-base titration and high-performance liquid…

NMR spectroscopy is currently a premier technique for structural elucidation of organic molecules. Quantitative NMR (qNMR) methodology has developed more slowly but is now widely accepted, especially in the areas of natural product and medicinal chemistry. However, many undergraduate students are not routinely exposed to this important concept.…

Improving the interest of high-school students towards chemistry (and science in general) is one of the goals of the Italian Ministry of Education. To this aim, we designed a context-based activity that actively involved students in six different laboratory experiences interconnected by a case study of the murder of Miss Scarlet, from the famous…

The classic technique for sulfate analysis in an undergraduate quantitative analysis lab involves precipitation as the barium salt with barium chloride, collection of the precipitate by gravity filtration using ashless filter paper, and removal of the filter paper by charring over a Bunsen burner. The entire process is time-consuming, hazardous,…

This study was designed to evaluate the effectiveness of student-generated videos as a supplement to teaching assistant (TA) instruction in an undergraduate organic chemistry laboratory. Three videos covering different aspects of lab instruction (experimental technique, use of instrumentation, and calculations) were produced using…

A series of undergraduate laboratory experiments that utilize reversed-phase HPLC separation, inductively coupled plasma spectroscopy (ICP), and scanning electron microscopy with energy dispersive spectroscopy (SEM-EDS) are described for the analysis of commercial sunscreens. The active ingredients of many sunscreen brands include zinc or titanium…

We have developed a process-oriented chemistry laboratory curriculum for non-science majors. The purpose of this study is both to explore university students' understanding of chemistry processes and to evaluate the quality of evidence students use to support their claims regarding chemistry processes in a process-oriented chemistry laboratory…

Many small-molecule antioxidants found in whole fruits and vegetables are analyzed and identified in this laboratory module for upper-division biochemistry courses. During this experiment, students develop their knowledge of the bioactivity of fruit and vegetable products while learning techniques to identify vitamins and nutritionally derived…

Engaging undergraduates in the environmental consequences of fossil fuel usage primes them to consider their own anthropogenic impact, and the benefits and trade-offs of converting to renewable fuel strategies. This laboratory activity explores the potential contaminants (both inorganic and organic) present in the raw fuel and solid waste…

This work describes a single-session laboratory experiment devoted to teaching the principles of factorial experimental design. Students undertook the rational optimization of a luminol oxidation reaction, using a two-level experiment that aimed to create a long-lasting bright emission. During the session students used only simple glassware and…

Metabolomics applies multivariate statistical analysis to sets of high-resolution spectra taken over a population of biologically derived samples. The objective is to distinguish subpopulations within the overall sample population, and possibly also to identify biomarkers. While metabolomics has become part of the standard analytical toolbox in…