Nowadays, the deterioration of education quality catches on global attention in both policy and practice. The main purpose of this study was to explore the influence of politics on quality management practices in the secondary education of the Southern Nations, Nationalities, and People's Region (SNNPR) of Ethiopia. This study utilized a multi-case study design with a purposive sampling technique to draw data from experts from the Ministry, regional education bureau, zonal education department, and woreda education offices. To that end, 18 experts were recruited to participate in interviews. The data gathered from interviewees were analyzed using NVivo 8 version combined with thematic data analysis procedures. The study revealed that the political practices of the country have been affecting the internal administration of the education system in three areas: by nominating educational managers at different levels, by forming One-to-Five Networks at different echelons, and by offering the mandates to avoid dropout and repetition. The study concluded that politics influenced the autonomy of educational institutions and their quality management practices in secondary education. Thus, the government should revisit its practices on education and allow educators manage their educational administration and organization business.