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Lee, Grace; Disterhoft, John F.; Kuo, Amy G. – Learning & Memory, 2006
A common cellular alteration, reduced post-burst afterhyperpolarization (AHP) in CA1 neurons, is associated with acquisition of the hippocampus-dependent tasks trace eyeblink conditioning and the Morris water maze. As a similar increase in excitability is correlated with these two learning paradigms, we sought to determine the interactive…
Descriptors: Behavioral Science Research, Conditioning, Neurological Organization, Brain
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Metherate, Raju – Learning & Memory, 2004
Acetylcholine release in sensory neocortex contributes to higher-order sensory function, in part by activating nicotinic acetylcholine receptors (nAChRs). Molecular studies have revealed a bewildering array of nAChR subtypes and cellular actions; however, there is some consensus emerging about the major nAChR subtypes and their functions in…
Descriptors: Auditory Perception, Stimulation, Biochemistry, Neurology