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Direct linkRagozzino, Michael E.; Choi, Daniel – Learning & Memory, 2004
The present studies explored the role of the medial striatum in learning when task contingencies change. Experiment 1 examined whether the medial striatum is involved in place reversal learning. Testing occurred in a modified cross-maze across two consecutive sessions. Injections of the local anesthetic, bupivacaine, into the medial striatum, did…
Descriptors: Nonverbal Learning, Biochemistry, Neurological Impairments, Behavioral Science Research
Chudasama, Yogita; Dalley, Jeffrey W.; Nathwani, Falgyni; Bouger, Pascale; Robbins, Trevor W. – Learning & Memory, 2004
Two experiments examined the effects of reductions in cortical cholinergic function on performance of a novel task that allowed for the simultaneous assessment of attention to a visual stimulus and memory for that stimulus over a variable delay within the same test session. In the first experiment, infusions of the muscarinic receptor antagonist…
Descriptors: Aging (Individuals), Visual Stimuli, Short Term Memory, Attention
Vuckovich, Joseph A.; Semel, Mara E.; Baxter, Mark G. – Learning & Memory, 2004
A recent study suggests that lesions to all major areas of the cholinergic basal forebrain in the rat (medial septum, horizontal limb of the diagonal band of Broca, and nucleus basalis magnocellularis) impair a spatial working memory task. However, this experiment used a surgical technique that may have damaged cerebellar Purkinje cells. The…
Descriptors: Neurological Impairments, Animals, Short Term Memory, Spatial Ability
