The current system of ethical oversight in the United States is based on Institutional Review Board (IRB) review. The system was established in response to well-known and egregious mistreatment of subjects in both biomedical and social and behavioral research. In the decades since the research regulations were enacted, reaction to the burden of…

Since the end of the Second World War, the United States has developed the world's preeminent system for biomedical research, one that has given rise to revolutionary medical advances as well as a dynamic and innovative business sector generating high-quality jobs and powering economic output and exports for the U.S. economy. However, there is a…

Animal models are extensively used in genetics, neuroscience and biomedical research. Recent studies illustrate the usefulness and the challenges of research utilising genetically engineered mice to explore the developmental biology of Down syndrome. These studies highlight many of the issues at the centre of what we understand about Down…

Discusses a General Accounting Office report that criticizes the National Institute of Health's system of funding biomedical research for, among other things, not ensuring priority to the most deserving projects. (MLH)

Paper delivered to the the Council of Academic Societies, Chicago, Illinois, February 1970. (IR)

Some of the uses of mathematics in biomedicine are listed and the problems involved in interdisciplinary biomathematical research are discussed. (MP)

A policy statement drafted by the Association of American Medical Colleges is presented that reviews the goals, environment, and mechanisms of support of biomedical and behavioral research.

This survey is intended as an aid in assessing the magnitude and character of the nonfederal contribution to health research, in particular the present availability of alternative nonfederal funding sources at doctoral institutions (the prime locus of the nation's biomedical research effort), and to elicit from institutional representatives their…

The fourth in a series of annual reports assessing the role of and need for federal training programs in the biomedical and behavioral sciences is presented. Highlights of this 1978 report include: (1) the results of surveys of the chairpersons of 1,324 basic biomedical science departments and 474 behavioral science departments in Ph.D.-granting…