We have developed a semester-long laboratory project for an undergraduate immunology course in which students study multiple aspects of macrophage biology including differentiation from progenitors in the bone marrow, activation upon stimulation with microbial ligands, expression of cell surface markers, and modulation of cytokine production. In…

Next-generation sequencing (NGS)-based methods are revolutionizing biology. Their prevalence requires biologists to be increasingly knowledgeable about computational methods to manage the enormous scale of data. As such, early introduction to NGS analysis and conceptual connection to wet-lab experiments is crucial for training young scientists.…

Many studies have shown a decrease in scientific interest with an increase in age. Since interest is linked to a high degree of deep-level learning, it is of great relevance to foster interest in science. This study investigates interest in biology from 7th, 9th, and 12th grade students in Germany (N=257). Results show a significantly lower…

Scientific inquiry requires the replication of results in experimental studies. Recent studies draw a severe picture on the need of replication and the difficulties in replicating already published studies. As replicated confirmation of results is the basis of scientific and medical research, there may be a need to introduce the topic of…

Course-based undergraduate research is promoted as an equitable strategy for providing the benefits of research experiences to a larger, more diverse population of students pursuing science degrees. Here, we report the impacts of course-based research on the self-efficacy and future goals of students enrolled in introductory biology courses at a…

This study was conducted within the scope of the General Biology Laboratory II course, which was taught in the Science Teaching Department in the Spring semester of the 2016-2017 academic year. The study group consisted of 40 teacher candidates in their second year in the Science Teaching Department at a state university in Konya. The purpose of…

The purpose of this study was twofold: (1) to determine the effectiveness of virtual laboratories relative to traditional or blended laboratories in the attainment of conceptual knowledge and skill in microscopy; and (2) to explore how such technologies are integrated in real world classrooms. Four sections of a non-major's introductory biology…

Enzymatic activity is at the core of biological reactions. Understanding them and the chemical and environmental factors that affect reaction rates is critical for biology students. The laboratory experiment proposed here investigated these concepts, while requiring students to document, graph data, analyse results using statistics, and…

Although research and new technologies have introduced different ways of observing microorganisms, including scanning and electron microscopy, these methods are expensive and require equipment that is typically not found in a middle school classroom. The transmission-through-dye technique (TTD; Gregg et al., 2010), a new optical microscopy method…

Chilling is a cost-effective and safe method of immobilising flies in "Drosophila" experiments. However, should condensation form on the plate, it would be fatal to the flies. Here we describe a modified cooling method using reusable commercial ice pack(s) (ca. 400 ml, 2-3 cm tall) rather than crushed ice. The ice pack is covered with a…

Two problems at two different abstraction levels of computational biology are studied. At the molecular level, efficient pattern matching algorithms in DNA sequences are presented. For gene order data, an efficient data structure is presented capable of storing all gene re-orderings in a systematic manner. A common characteristic of presented…

Cell and developmental processes are complex, and profoundly dependent on spatial relationships that change over time. Innovative educational or teaching strategies are always needed to foster deep comprehension of these processes and their dynamic features. However, laboratory exercises in cell and developmental biology at the undergraduate level…

Decreasing interest in Science among students, confirmed by several investigations, calls for the need to revise the contents of the curricula for Science subjects, including Biology. Modern Biology curricula should not only contain key biological concepts but also provide a teacher with sufficient space to develop students' competencies of…

Student learning in biology may be impaired by instructional environments that emphasize technical methodology over analysis. We hypothesized that time gained by experimenting with accurate computer simulations could be used to engage students in analytical, creative learning. The effects of treatments that combined a week of simulated lab…

A lesson plan on the phylum Tardigrada is presented in a storytelling workbook that introduces the evolutionary concepts of adaptive radiation, speciation, divergence, and "tree-thinking" through narrative, transitional art, contemplative coloring, and data searches, which can be enhanced with microscopy wet labs. Students gain insight…