Governance and regulation of the use of live animals in research and teaching is examined in Australia, Malaysia, Indonesia, the Philippines, Singapore, Thailand, China, Japan and India. A comparison of the systems in different countries will enable the determination of best practice and fit-forpurpose regulation. The most comprehensive government…

To fully appreciate genetics, one must understand the link between genotype (DNA sequence) and phenotype (observable characteristics). Advances in high-throughput genomic sequencing technologies and applications, so-called "-omics," have made genetic sequencing readily available across fields in biology from applications in…

Scientific advances in genetic analysis have been made possible in recent years by technical developments in computational biology, or bioinformatics. Bioinformatics has opened up the human genome to diverse analyses involving automated laboratory hardware and machine learning algorithms and software. As part of an emerging field of social…

The Challenges and Opportunities for Education About Dual Use Issues in the Life Sciences workshop was held to engage the life sciences community on the particular security issues related to research with dual use potential. More than 60 participants from almost 30 countries took part and included practicing life scientists, bioethics and…

The philosophy of biology today is one of the most exciting areas of philosophy. It looks critically across the life sciences, teasing out conceptual issues and difficulties bringing to bear the tools of philosophical analysis to achieve clarification and understanding. This essay surveys work in all of the major directions of research:…

Reviews history of "recombinant DNA" research, including early experiments and origins of bioethical debates between concerned scientists. Discusses National Institutes of Health (NIH) guidelines and accompanying Environmental Impact statement regarding recombinant DNA research and possibilities of human error covered by neither…

Addresses the most popular models currently being chosen for biological research and the reasons behind those choices. Among the current favorites are zebra fish, fruit flies, mice, monkeys, and yeast. Concludes with a brief examination of the ethical issues involved, and why some animals may need to be replaced in research with model systems.…

Examines a specific experiment in view of its ethical problems and possible scientific advances. (LS)

Describes the results of a survey using an open-form questionnaire to determine student attitudes toward animal experimentation. Results indicate that children's views about animal experimentation for research depend on the purpose of the research. More than half felt experimentation for pure research is inappropriate. (DDR)

Most biology teachers implement animal dissection (real or virtual) and often lead discussions on research involving animal subjects. Such activities provide excellent opportunities to explore ideas about ethical conduct in the care and use of animals. The challenge for teachers is to present information about animal care and use that enables…

The agencies listed in this document are amending the Federal Policy for the Protection of Human Subjects, which was published in the Federal Register on June 18, 1991, to change all references to the Office for Protection from Research Risks (OPRR) to the Office for Human Research Protections (OHRP); revise the footnote found at the end of…

Thirteen articles in this special issue discuss aging theories, biomarkers of aging, aging research, disease, cancer biology, Alzheimer's disease, stress, oxidation of proteins, gene therapy, service delivery, biogerontology, and ethics and aging research. (SK)

This article explains how animals are used in research in an effort to counteract animal rights literature. Reveals how medical professionals and others trained in scholarship have misquoted the scientific literature to bolster their claims against the utility of animal research. (PR)

Examines the ethics, economics, manpower needs and future regulation of biotechnology. Discusses the new tests of the basic premise of the universality of knowledge gained from university research as attempts are made to patent and temporarily withhold publication of proprietary discoveries made with taxpayer support. (CW)

The board that advises the Secretary of HEW on ethics has given a qualified approval for further review of federal funding for research on human embryos conceived in the laboratory. Issues and concerns that influenced the board's decision are addressed. (JMD)