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Troisi, Joseph R., II; Bryant, Erin; Kane, Jennifer – Psychological Record, 2012
Extinction and recovery of the discriminative stimulus effects of nicotine (0.3 mg/kg) was investigated with a devalued food reinforcer (rats sated). Sixteen rats were trained in a counterbalanced one manipulandum (nose-poke) drug discrimination procedure with the roles of nicotine and saline counterbalanced as S[superscript D] and S[superscript…
Descriptors: Therapy, Reinforcement, Smoking, Stimuli
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Chang, Chun-hui; Maren, Stephen – Learning & Memory, 2011
It has been suggested that reduced infralimbic (IL) cortical activity contributes to impairments of fear extinction. We therefore explored whether pharmacological activation of the IL would facilitate extinction under conditions it normally fails (i.e., immediate extinction). Rats received auditory fear conditioning 1 h before extinction training.…
Descriptors: Fear, Brain Hemisphere Functions, Animals, Drug Use
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Stableford, William; And Others – American Journal of Orthopsychiatry, 1976
Descriptors: Behavior Change, Case Studies, Drug Therapy, Drug Use