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Interagency Autism Coordinating Committee, 2014
Each year, the Interagency Autism Coordinating Committee (IACC) releases its annual list of scientific advances that represent significant progress in the field. The 20 studies selected have given new insight into the complex causes of autism and potential risk factors, studied clues that could lead to earlier diagnosis, and evaluated promising…
Descriptors: Autism, Research, Etiology, Clinical Diagnosis
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Stevens, Hanna E. – Journal of the American Academy of Child & Adolescent Psychiatry, 2009
There are several researches that demonstrate the importance of glia for child psychiatric disorders. One study found that levels of two astrocyctic proteins are altered in the brains of adults with autism while another research found that changes in glia are induced by some early adverse experiences.
Descriptors: Brain, Mental Disorders, Child Health, Children
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Fatemi, S. Hossein; Reutiman, Teri J.; Folsom, Timothy D.; Thuras, Paul D. – Journal of Autism and Developmental Disorders, 2009
Gamma-aminobutyric acid A (GABA[subscript A]) receptors are ligand-gated ion channels responsible for mediation of fast inhibitory action of GABA in the brain. Preliminary reports have demonstrated altered expression of GABA receptors in the brains of subjects with autism suggesting GABA/glutamate system dysregulation. We investigated the…
Descriptors: Autism, Pathology, Brain, Cognitive Processes
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Qiu, Anqi; Adler, Marcy; Crocetti, Deana; Miller, Michael I.; Mostofsky, Stewart H. – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: Basal ganglia abnormalities have been suggested as contributing to motor, social, and communicative impairments in autism spectrum disorder (ASD). Volumetric analyses offer limited ability to detect localized differences in basal ganglia structure. Our objective was to investigate basal ganglia shape abnormalities and their association…
Descriptors: Autism, Psychomotor Skills, Males, Brain
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Pijnacker, Judith; Geurts, Bart; van Lambalgen, Michiel; Kan, Cornelis C.; Buitelaar, Jan K.; Hagoort, Peter – Neuropsychologia, 2009
While autism is one of the most intensively researched psychiatric disorders, little is known about reasoning skills of people with autism. The focus of this study was on defeasible inferences, that is inferences that can be revised in the light of new information. We used a behavioral task to investigate (a) conditional reasoning and (b) the…
Descriptors: Autism, Inferences, Thinking Skills, Task Analysis
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van Kooten, Imke A. J.; Palmen, Saskia J. M. C.; von Cappeln, Patricia; Steinbusch, Harry W. M.; Korr, Hubert; Heinsen, Helmut; Hof, Patrick R.; van Engeland, Herman; Schmitz, Christoph – Brain, 2008
Abnormalities in face perception are a core feature of social disabilities in autism. Recent functional magnetic resonance imaging studies showed that patients with autism could perform face perception tasks. However, the fusiform gyrus (FG) and other cortical regions supporting face processing in controls are hypoactive in patients with autism.…
Descriptors: Autism, Visual Perception, Brain, Neurological Organization
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Wallace, Gregory L.; Anderson, Mike; Happe, Francesca – Journal of Autism and Developmental Disorders, 2009
Speed of information processing, as measured by inspection time (IT), is a robust predictor of intellectual functioning. However, among individuals with autism and low IQ scores, IT has been reported to be discrepantly fast, and equal to that of high IQ typically developing children (Scheuffgen et al. in "Dev Psychopathol" 12: 83-90, 2000). The…
Descriptors: Autism, Intelligence Quotient, Cognitive Processes, Correlation
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Groen, Wouter B.; van Orsouw, Linda; ter Huurne, Niels; Swinkels, Sophie; van der Gaag, Rutger-Jan; Buitelaar, Jan K.; Zwiers, Marcel P. – Journal of Autism and Developmental Disorders, 2009
The perceptual pattern in autism has been related to either a specific localized processing deficit or a pathway-independent, complexity-specific anomaly. We examined auditory perception in autism using an auditory disembedding task that required spectral and temporal integration. 23 children with high-functioning-autism and 23 matched controls…
Descriptors: Auditory Stimuli, Autism, Auditory Perception, Cognitive Processes
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Hoffman, Ellen J.; State, Matthew W. – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: This review considers the impact of chromosomal studies on the understanding of childhood neuropsychiatric syndromes, highlighting key discoveries, advances in technology, and new challenges faced by clinicians trying to interpret recent findings. Method: We review the literature on the genetics of child psychiatric disorders, including…
Descriptors: Attention Deficit Hyperactivity Disorder, Investigations, Schizophrenia, Emotional Disturbances
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Sahyoun, Cherif P.; Belliveau, John W.; Mody, Maria – Brain and Cognition, 2010
The current study investigated the neurobiological role of white matter in visuospatial versus linguistic processing abilities in autism using diffusion tensor imaging. We examined differences in white matter integrity between high-functioning children with autism (HFA) and typically developing controls (CTRL), in relation to the groups' response…
Descriptors: Semantics, Autism, Integrity, Pictorial Stimuli
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Keary, Christopher J.; Minshew, Nancy J.; Bansal, Rahul; Goradia, Dhruman; Fedorov, Serguei; Keshavan, Matcheri S.; Hardan, Antonio Y. – Journal of Autism and Developmental Disorders, 2009
The corpus callosum has recently been considered as an index of interhemispheric connectivity. This study applied a novel volumetric method to examine the size of the corpus callosum in 32 individuals with autism and 34 age-, gender- and IQ-matched controls and to investigate the relationship between this structure and cognitive measures linked to…
Descriptors: Autism, Cognitive Tests, Cognitive Processes, Brain
Muller, Eve – Project Forum, 2011
The purpose of this document is to provide a brief overview of how links are being developed between the rapidly expanding field of neuroscience and the practice of special education. The first part of the document introduces definitions and terminology, provides an overview of how findings from neuroscience are being applied to the field of…
Descriptors: Colleges, Disabilities, Special Education, Higher Education
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Kouijzer, Mirjam E. J.; van Schie, Hein T.; de Moor, Jan M. H.; Gerrits, Berrie J. L.; Buitelaar, Jan K. – Research in Autism Spectrum Disorders, 2010
Effects of neurofeedback treatment were investigated in children with autism spectrum disorders (ASD). Sixty percent of the participants in the treatment group successfully reduced excessive theta power during neurofeedback treatment. Reduction of theta power was confirmed by pre- and post-QEEG measures. Parents of participants in the…
Descriptors: Control Groups, Autism, Communication Skills, Neurological Impairments
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Belmonte, Matthew K.; Mazziotta, John C.; Minshew, Nancy J.; Evans, Alan C.; Courchesne, Eric; Dager, Stephen R.; Bookheimer, Susan Y.; Aylward, Elizabeth H.; Amaral, David G.; Cantor, Rita M.; Chugani, Diane C.; Dale, Anders M.; Davatzikos, Christos; Gerig, Guido; Herbert, Martha R.; Lainhart, Janet E.; Murphy, Declan G.; Piven, Joseph; Reiss, Allan L.; Schultz, Robert T.; Zeffiro, Thomas A.; Levi-Pearl, Susan; Lajonchere, Clara; Colamarino, Sophia A. – Journal of Autism and Developmental Disorders, 2008
Data sharing in autism neuroimaging presents scientific, technical, and social obstacles. We outline the desiderata for a data-sharing scheme that combines imaging with other measures of phenotype and with genetics, defines requirements for comparability of derived data and recommendations for raw data, outlines a core protocol including…
Descriptors: Autism, Genetics, Measurement Techniques, Data Analysis
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Boyd, Brian A.; McBee, Matthew; Holtzclaw, Tia; Baranek, Grace T.; Bodfish, James W. – Research in Autism Spectrum Disorders, 2009
This study examined the relationship between repetitive behaviors and sensory processing issues in school-aged children with high functioning autism (HFA). Children with HFA (N = 61) were compared to healthy, typical controls (N = 64) to determine the relationship between these behavioral classes and to examine whether executive dysfunction…
Descriptors: Autism, Antisocial Behavior, Behavior Problems, Cognitive Ability
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