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Direct linkHernández-Matias, Arturo; Bermúdez-Rattoni, Federico; Osorio-Gómez, Daniel – Learning & Memory, 2021
It has been reported that during chemotherapy treatment, some patients can experience nausea before pharmacological administration, suggesting that contextual stimuli are associated with the nauseating effects. There are attempts to reproduce with animal models the conditions under which this phenomenon is observed to provide a useful paradigm for…
Descriptors: Context Effect, Animals, Drug Therapy, Brain Hemisphere Functions
Darvas, Martin; Fadok, Jonathan P.; Palmiter, Richard D. – Learning & Memory, 2011
Two-way active avoidance (2WAA) involves learning Pavlovian (association of a sound cue with a foot shock) and instrumental (shock avoidance) contingencies. To identify regions where dopamine (DA) is involved in mediating 2WAA, we restored DA signaling in specific brain areas of dopamine-deficient (DD) mice by local reactivation of conditionally…
Descriptors: Animals, Classical Conditioning, Genetics, Biochemistry
Wolpaw, Jonathan R.; Chen, Xiang Yang – Learning & Memory, 2006
Operant conditioning of the H-reflex, the electrical analog of the spinal stretch reflex, is a simple model of skill acquisition and involves plasticity in the spinal cord. Previous work showed that the cerebellum is essential for down-conditioning the H-reflex. This study asks whether the cerebellum is also essential for maintaining…
Descriptors: Psychomotor Skills, Operant Conditioning, Human Body, Animals
