Objectives: Certain heart conditions and diseases are common in Down syndrome (DS; trisomy 21), but their role in early onset dementia that is prevalent in older adults with DS has not been evaluated. To address this knowledge gap, we conducted a study of risk factors for low neurocognitive/behavioral scores obtained with a published dementia test…

Background: Medical problems are described in a population of persons with Down syndrome. Health surveillance is compared to the recommendations of national guidelines. Method: Case records from the specialised and primary healthcare and disability services were analysed. Results: A wide spectrum of age-specific medical and surgical problems was…

The study demonstrates the Fenton reaction, which is carried out using the Fenton reagent that is used for groundwater and soil remediation. The Fenton reaction can be implicated in DNA damage, Alzheimer's disease, cardiovascular disease and ageing in general.

The relationship between poor health and cognitive impairment is not fully understood yet. People with Down syndrome are prone to a number of health problems, including congenital heart defect, visual impairment, hearing loss, autoimmune diseases, epilepsy, early-onset Alzheimer's disease and intellectual disability. Our aim was to assess the…

Strategies to fix America's ailing health-care system seemed to fly off the presses every month in 2007. Doctors, journalists, and policymakers clamored to have their say, as did supporters and opponents of the controversial life-extension movement. These top trends, which registered in 2006 as well, and will only balloon in this election year,…

Down syndrome (DS) is characterized by increased mortality rates, both during early and later stages of life, and age-specific mortality risk remains higher in adults with DS compared with the overall population of people with mental retardation and with typically developing populations. Causes of increased mortality rates early in life are…

In 2004, the Women's Sports Foundation published the first edition of "Her Life Depends On It" (Don Sabo, Kathleen E. Miller, Merrill J. Melnick, and Leslie Heywood). At that time, it was clear that evidence-based research confirmed that regular physical activity and sport provides the critical foundation, in no small part, that allows girls and…