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Experiences of Supporting People with Down Syndrome and Alzheimer's Disease in Aged Care and Family Environments
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Carling-Jenkins, Rachel; Torr, Jennifer; Iacono, Teresa; Bigby, Christine – Journal of Intellectual & Developmental Disability, 2012
Background: Research addressing the experiences of families of adults with Down syndrome and Alzheimer's disease in seeking diagnosis and gaining support is limited. The aim of this study was to gain a greater understanding of these processes by exploring the experiences of families and carers in supporting people with Down syndrome and…
Descriptors: Alzheimers Disease, Down Syndrome, Aging (Individuals), Older Adults
A[Beta] Deposits in Older Non-Demented Individuals with Cognitive Decline Are Indicative of Preclinical Alzheimer's Disease
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Villemagne, V. L.; Pike, K. E.; Darby, D.; Maruff, P.; Savage, G.; Ng, S.; Ackermann, U.; Cowie, T. F.; Currie, J.; Chan, S. G.; Jones, G.; Tochon-Danguy, H.; O'Keefe, G.; Masters, C. L.; Rowe, C. C. – Neuropsychologia, 2008
Approximately 30% of healthy persons aged over 75 years show A[beta] deposition at autopsy. It is postulated that this represents preclinical Alzheimer's disease (AD). We evaluated the relationship between A[beta] burden as assessed by PiB PET and cognitive decline in a well-characterized, non-demented, elderly cohort. PiB PET studies and…
Descriptors: Alzheimers Disease, Cognitive Tests, Older Adults, Memory