Objective: This study examined if empathy was a significant moderator of several empirically established risk factors for sexual violence perpetration among college men. Participants: Data are from 544 college men who participated in a longitudinal study from 2008 to 2011 at a large, public university. Methods: Participants completed a self-report survey in their first through fourth years in college. A series of generalized linear models were conducted using sexual violence risk factors and empathy during the sophomore year as predictors of sexual violence perpetration frequency during junior year. Results: Empathy was found to be a significant moderator of six out of the 10 sexual violence risk factors tested, such that high levels of empathy were associated with lower sexual violence perpetration rates among high-risk males. Conclusion: Additional research, including the measurement and evaluation of empathy in implementation of college sexual violence prevention and intervention efforts, should be undertaken.