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Download full textInteragency Autism Coordinating Committee, 2023
Each year, the Interagency Autism Coordinating Committee (IACC) releases a list of scientific advances that represent significant progress in the field of autism research. The "Summary of Advances" provides short, plain language summaries of the top research breakthroughs selected by the IACC from a pool of research articles nominated by…
Descriptors: Autism Spectrum Disorders, Research, Screening Tests, Clinical Diagnosis
Direct linkRobinson-Neal, Andree – Exceptional Parent, 2009
As a parent of a son with an autism spectrum disorder (ASD), the author was aware of the various theories regarding genetic predictors, toxic and heavy metal exposure, and immunization after-effects. However, she had not seriously considered that genetics or a history of emotional and psychological challenges in her family line could have been…
Descriptors: Autism, Genetics, Sons, Disabilities
Peer reviewedSpek, Annelies A.; Wouters, Saskia G. M. – Research in Autism Spectrum Disorders, 2010
Several recent studies have demonstrated a genetical overlap between autism and schizophrenia. However, at a behavioral level it remains unclear which features can validly distinguish adults with autism from an adult schizophrenia group. To this end, the present study compared 21 individuals with the autistic disorder and 21 individuals with…
Descriptors: Schizophrenia, Autism, Genetics, Adults
Schirmbeck, Frederike; Georgi, Alexander; Strohmaier, Jana; Schmael, Christine; Boesshenz, Katja V.; Muhleisen, Thomas W.; Herms, Stefan; Hoffmann, Per; Jamra, Rami Abou; Schumacher, Johannes; Maier, Wolfgang; Propping, Peter; Nothen, Markus M.; Cichon, Sven; Rietschel, Marcella; Schulze, Thomas G. – Journal of Autism and Developmental Disorders, 2008
Whereas "Dysbindin" is considered a schizophrenia vulnerability gene, there is no consistency of findings. Phenotype refinement approaches may help to increase the genetic homogeneity and thus reconcile conflicting results. Premorbid adjustment (PMA) has been suggested to aid the phenotypic dissection. Gornick et al. ("J Autism Dev…
Descriptors: Schizophrenia, Patients, Genetics, Foreign Countries
Gothelf, Doron; Frisch, Amos; Michaelovsky, Elena; Weizman, Abraham; Shprintzen, Robert J. – Journal of Mental Health Research in Intellectual Disabilities, 2009
Velocardiofacial syndrome (VCFS), also known as DiGeorge, conotruncal anomaly face, and Cayler syndromes, is caused by a microdeletion in the long arm of Chromosome 22. We review the history of the syndrome from the first clinical reports almost half a century ago to the current intriguing molecular findings associating genes from the…
Descriptors: Schizophrenia, Mental Disorders, Learning Disabilities, Risk
Raznahan, A.; Joinson, C.; O'Callaghan, F.; Osborne, J. P.; Bolton, P. F. – Journal of Intellectual Disability Research, 2006
Background: Tuberous sclerosis (TS) is a multi- system disorder with complex genetics. The neurodevelopmental manifestations of TS are responsible for considerable morbidity. The prevalence of epilepsy and intellectual disabilities among individuals with TS have been well described. Ours is the first study that explores the prevalence and pattern…
Descriptors: Psychopathology, Developmental Disabilities, Mental Retardation, Genetics
Rutter, Michael; Kim-Cohen, Julia; Maughan, Barbara – Journal of Child Psychology and Psychiatry, 2006
The possible mechanisms involved in continuities and discontinuities in psychopathology between childhood and adult life are considered in relation to the findings from systematic, prospective, long-term longitudinal studies. Findings on schizophrenia, neurodevelopmental disorders, emotional disturbances, antisocial behaviour and substance abuse…
Descriptors: Substance Abuse, Schizophrenia, Emotional Disturbances, Psychopathology
fMRI Correlates of State and Trait Effects in Subjects at Genetically Enhanced Risk of Schizophrenia
Whalley, Heather C.; Simonotto, E.; Flett, S.; Marshal, I.; Ebmeier, K. P.; Owens, D. G. C.; Goddard, N. H.; Johnstone, E. C.; Lawrie, S. M. – Brain, 2004
Schizophrenia is a highly heritable disorder that typically develops in early adult life. Structural imaging studies have indicated that patients with the illness, and to some extent their unaffected relatives, have subtle deficits in several brain regions, including prefrontal and temporal lobes. It is, however, not known how this inherited…
Descriptors: Schizophrenia, Genetics, Correlation, Heredity
Schopler, Eric; Loftin, Julie – J Abnorm Psychol, 1969
Research supported in part by General Research Support Award No. FR-05406 from the United States Public Health Service.
Descriptors: Adults, Cognitive Processes, Concept Formation, Genetics
Biswas, Parthasarathy; Malhotra, Savita; Malhotra, Anil; Gupta, Nitin – Journal of Indian Association for Child and Adolescent Mental Health, 2006
Background: Childhood onset schizophrenia (COS) is a rare disorder. Comparative data on the effect of differential age of onset on clinical profile in schizophrenia are very few. Method: Subjects with COS (n = 15), adolescence onset schizophrenia (AdOS, n = 20) and adulthood onset schizophrenia (AOS, n = 20) were compared on socio-demographic,…
Descriptors: Schizophrenia, Intelligence Quotient, Psychopathology, Children
