Background: In intellectual disability, the cognitive delay is observed during developmental age, whereas in dementia, cognitive decline occurs during post-developmental period. So far, the risk of dementia in people with intellectual disability, excluding those with Down syndrome, is poorly known. Method: We screened dementia signs in a study…

Individuals diagnosed with autism spectrum disorder (ASD) have a higher probability of developing co-occurring mental or physical health conditions. However, little is known about how these health conditions develop and impact the lives of the adult ASD population. This paper reviewed existing studies concerning factors affecting the health status…

Purpose: The objective of this study was to use cross-sectional, nationally representative data to examine the relationship between self-reported hearing impairment and undetected diabetes, hypertension, hypercholesterolemia, and chronic kidney disease. Method: We analyzed the National Health and Nutrition Examination Survey for the years…

Descriptions of individuals with Williams syndrome (WS) and co-morbid major depressive disorder (MDD) with psychotic features have not appeared in the literature. In addition to reviewing previous reports of psychotic symptoms in persons with WS, this paper introduces clinical histories and therapeutic management strategies for three previously…

This paper considers the use of identity boxes as a data collection method to elicit experiences. Participants were asked to respond to questions using objects to represent their answers. The rationale for using identity boxes was to allow for a more embodied, less textual approach. The identity boxes were then also used to create an artistic…

Creativity is considered to be one of the most important characteristics that humans possess. It emerges from fundamental cognitive operations and the activation of specific brain regions. In several neurological disorders, such as frontotemporal dementia (FTD) and Parkinson's disease (PD), creativity plays an important role in diagnosis and…

The prevalence of autism spectrum disorder (ASD) in adults is estimated to be at least 1% (Brugha et al., 2011), yet almost all ASD research focuses on children. Adult intervention studies, in particular, are few in number and poor in quality (Bishop-Fitzpatrick, Minshew, & Eack, 2013), and support networks for adults with ASD are much more…

Although the better-educated are more likely to practice healthy behaviors when measured at one point in time, there is no clear evidence regarding whether more educated people are more likely to initiate healthy behavior changes in the face of new chronic conditions and whether they are better able to adhere to these healthy changes, once made. I…

The purpose of this study is to compare the prevalence and types of diseases (International Classification of Mental and Behavioural Disorders, 10th Edition codes K20-K93) relating to the gastrointestinal tract in a clinical sample of 89 individuals diagnosed as children with atypical autism/pervasive developmental disorder not otherwise specified…

The congenital disorders of glycosylation (CDG) are a rapidly growing group of inborn errors of metabolism that result from defects in the synthesis of glycans. Glycosylation is a major post-translational protein modification and an estimated 2% of the human genome encodes proteins for glycosylation. The molecular bases for the current 60…

This "2018-2019 Interagency Autism Coordinating Committee (IACC) Strategic Plan Update" is the work of the IACC membership that was appointed under the Autism CARES Act of 2014. The Committee agreed that the "2016-2017 IACC Strategic Plan" reflected a comprehensive review of the state of the field and provided a set of 23 new…

Autism is a developmental disability that provides special challenges to families, schools, and adult support systems. An additional area that is affected by the symptoms of autism is medicine. The deficits associated with autism in the areas of communication and social skills, as well as the prevalence of challenging behavior can interfere with…

Surveys empirical literature pertaining to phobias of blood, injury, or illness (BII); defines BII phobia as selectively associated with vasovagal fainting response upon exposure to phobic stimuli. Presents clinical, demographic, and etiological information from 15 BII phobics and suggests that BII phobia warrants diagnostic category separate from…

Neurological changes of Alzheimer's disease have been consistently documented in individuals with Down syndrome 35 years of age or older suggesting a genetic relationship between the conditions. The paper discusses the diagnosis of Alzheimer's disease, its progressive behavioral impact on persons with Down syndrome, and implications for services…

This fact sheet summarizes the interrelations of Down syndrome and Alzheimer disease in a question and answer format. The following questions are addressed: What is Alzheimer disease? Why is a relationship suggested between Down syndrome and Alzheimer disease? Is there a genetic link between Alzheimer disease and Down syndrome? Why is a…