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Direct linkBrianna Piro-Gambetti; Emily K. Schworer; Benjamin Handen; Masha Glukhovskaya; Sigan L. Hartley – Journal of Intellectual Disabilities, 2024
Adults with Down syndrome (DS) experience high risk for Alzheimer's disease (AD), but there is variability in the timing of transition from a cognitively stable state to prodromal AD and dementia. The present study examined the association between a modifiable lifestyle factor, employment complexity, and cognitive decline across two time points in…
Descriptors: Employment, At Risk Persons, Alzheimers Disease, Vocational Education
Hutchinson, Nick; Oakes, Peter – Journal of Applied Research in Intellectual Disabilities, 2011
Background: People with Down Syndrome are at significant risk of developing Alzheimer's disease as they get older and early assessment, diagnosis and intervention is essential. Neuro-psychological measures of cognitive functioning play an important part in the assessment process. The aim of the present study was to examine the concurrent criterion…
Descriptors: Down Syndrome, Adults, Alzheimers Disease, Cognitive Tests
Iacono, Teresa; Torr, Jennifer; Wong, Hui Yi – Research in Developmental Disabilities: A Multidisciplinary Journal, 2010
Studies into the effects of ageing on language in adults with Down syndrome (DS) have tended to rely on measures that lack sensitivity to change because they fail to explore across linguistic domains or rely on proxy reports. The study aim was to use measures of receptive and expressive language from studies of younger individuals with DS in…
Descriptors: Mental Age, Linguistics, Alzheimers Disease, Down Syndrome
Margallo-Lana, M. L.; Moore, P. B.; Kay, D. W. K.; Perry, R. H.; Reid, B. E.; Berney, T. P.; Tyrer, S. P. – Journal of Intellectual Disability Research, 2007
Background: The clinical and neuropathological features associated with dementia in Down's syndrome (DS) are not well established. Aims: To examine clinico-pathological correlations and the incidence of cognitive decline in a cohort of adults with DS. Method: A total of 92 hospitalized persons with DS were followed up from 1985 to December 2000.…
Descriptors: Adjustment (to Environment), Adults, Patients, Incidence
Hodgson, Lynne Gershenson; Cutler, Stephen J. – International Journal of Aging and Human Development, 2003
This study examined the correlates of symptom-seeking behavior for Alzheimer's disease (AD) among middle-aged persons. Symptom seeking, the tendency to search for signs of disease, is one manifestation of an individual's concern about developing AD. The data were obtained from a survey of two subsamples of 40-60 year old adults: 1) 108 adult…
Descriptors: Memory, Alzheimers Disease, Symptoms (Individual Disorders), Correlation
Montoro-Rodriguez, Julian; Kosloski, Karl; Montgomery, Rhonda J. V. – Gerontologist, 2003
Purpose: The goal of this study was to evaluate the practice-oriented model of service use (Yeatts, Crow, & Folts, 1992) relative to the more widely used behavioral model (Andersen, 1968) in its ability to explain the use of respite services by caregivers of Alzheimer's patients. Unlike the behavioral model, which focuses primarily on…
Descriptors: Rural Areas, Access to Health Care, Alzheimers Disease, Caregivers
