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Lifestyle Factors and Alzheimer's Disease in People with Down Syndrome
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Kenshole, Athena V.; Gallichan, Deanna; Pahl, Sabine; Clibbens, John – Journal of Applied Research in Intellectual Disabilities, 2017
Background: Lifestyle has previously been associated with the onset of Alzheimer's disease (AD) in the typically developing population, but research investigating this association in Down syndrome (DS) is limited. Method: Adults with DS and AD (n = 27) were compared to adults with DS without AD (n = 30) on physical activity, diet, weight, where…
Descriptors: Alzheimers Disease, Life Style, Down Syndrome, Adults
Positive Effects of Computer-Based Cognitive Training in Adults with Mild Cognitive Impairment
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Herrera, C.; Chambon, C.; Michel, B. F.; Paban, V.; Alescio-Lautier, B. – Neuropsychologia, 2012
Considering the high risk for individuals with amnestic Mild Cognitive Impairment (A-MCI) to progress towards Alzheimer's disease (AD), we investigated the efficacy of a non-pharmacological intervention, that is, cognitive training that could reduce cognitive difficulties and delay the cognitive decline. For this, we evaluated the efficacy of a…
Descriptors: Control Groups, Investigations, Intervention, Alzheimers Disease
Effects of Semantic Elaboration and Typicality on Picture Naming in Alzheimer Disease
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Morelli, Claudia A.; Altmann, Lori J. P.; Kendall, Diane; Fischler, Ira; Heilman, Kennneth M. – Journal of Communication Disorders, 2011
Purpose: Individuals with probable Alzheimer disease (pAD) are frequently impaired at picture naming. This study examined whether a semantic elaboration task would facilitate naming in pAD, and whether training either semantically typical or atypical stimulus items facilitated generalized improvement in picture naming and category generation…
Descriptors: Semantics, Alzheimers Disease, Pictorial Stimuli, Recognition (Psychology)
A Pilot Study of a Test for Visual Recognition Memory in Adults with Moderate to Severe Intellectual Disability
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Pyo, Geunyeong; Ala, Tom; Kyrouac, Gregory A.; Verhulst, Steven J. – Research in Developmental Disabilities: A Multidisciplinary Journal, 2010
Objective assessment of memory functioning is an important part of evaluation for Dementia of Alzheimer Type (DAT). The revised Picture Recognition Memory Test (r-PRMT) is a test for visual recognition memory to assess memory functioning of persons with intellectual disabilities (ID), specifically targeting moderate to severe ID. A pilot study was…
Descriptors: Severe Mental Retardation, Dementia, Recognition (Psychology), Visual Perception
The Effect of Acetyl-L-Carnitine Administration on Persons with Down Syndrome
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Pueschel, Siegfried M. – Research in Developmental Disabilities: A Multidisciplinary Journal, 2006
Since previous investigations reported improvements in cognition of patients with dementia after acetyl-L-carnitine therapy and since there is an increased risk for persons with Down syndrome to develop Alzheimer disease, this study was designed to investigate the effect of acetyl-L-carnitine administration on neurological, intellectual, and…
Descriptors: Down Syndrome, Alzheimers Disease, Adults, Psychological Testing
Linguistic Deterioration in Alzheimer's Senile Dementia and in Normal Aging.
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Emery, Olga Beattie – 1984
A study of language patterning as an indicator of higher cortical process focused on three matched comparison groups: normal pre-middle-aged, normal elderly, and elderly adults with senile dementia Alzheimer's type. In addition to tests of memory, level of cognitive function, and organic deficit, the formal aspects of language were analyzed in…
Descriptors: Adults, Age Differences, Aging (Individuals), Alzheimers Disease