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Direct linkMorelli, Claudia A.; Altmann, Lori J. P.; Kendall, Diane; Fischler, Ira; Heilman, Kennneth M. – Journal of Communication Disorders, 2011
Purpose: Individuals with probable Alzheimer disease (pAD) are frequently impaired at picture naming. This study examined whether a semantic elaboration task would facilitate naming in pAD, and whether training either semantically typical or atypical stimulus items facilitated generalized improvement in picture naming and category generation…
Descriptors: Semantics, Alzheimers Disease, Pictorial Stimuli, Recognition (Psychology)
Krinsky-McHale, Sharon J.; Devenny, Darlynne A.; Kittler, Phyllis; Silverman, Wayne – American Journal on Mental Retardation, 2008
Adults with Down syndrome and early stage Alzheimer's disease showed decline in their ability to selectively attend to stimuli in a multitrial cancellation task. They also showed variability in their performance over the test trials, whereas healthy participants showed stability. These changes in performance were observed approximately 2 years…
Descriptors: Alzheimers Disease, Dementia, Attention Span, Down Syndrome
Margallo-Lana, M. L.; Moore, P. B.; Kay, D. W. K.; Perry, R. H.; Reid, B. E.; Berney, T. P.; Tyrer, S. P. – Journal of Intellectual Disability Research, 2007
Background: The clinical and neuropathological features associated with dementia in Down's syndrome (DS) are not well established. Aims: To examine clinico-pathological correlations and the incidence of cognitive decline in a cohort of adults with DS. Method: A total of 92 hospitalized persons with DS were followed up from 1985 to December 2000.…
Descriptors: Adjustment (to Environment), Adults, Patients, Incidence
Ball, S. L.; Holland, A. J.; Huppert, F. A.; Treppner, P.; Watson, P.; Hon, J. – Journal of Intellectual Disability Research, 2004
Dementia because of Alzheimer's disease (AD) commonly affects older adults with Down's syndrome (DS). Methods are needed, with established concurrent and predictive validity, to facilitate the diagnostic assessment of dementia, when it is complicated by pre-existing intellectual disabilities (ID). We report on the reliability and validity of a…
Descriptors: Identification, Predictive Validity, Interrater Reliability, Alzheimers Disease
Pueschel, Siegfried M. – Research in Developmental Disabilities: A Multidisciplinary Journal, 2006
Since previous investigations reported improvements in cognition of patients with dementia after acetyl-L-carnitine therapy and since there is an increased risk for persons with Down syndrome to develop Alzheimer disease, this study was designed to investigate the effect of acetyl-L-carnitine administration on neurological, intellectual, and…
Descriptors: Down Syndrome, Alzheimers Disease, Adults, Psychological Testing
Perkins, Elizabeth A.; Small, Brent J. – Journal of Policy and Practice in Intellectual Disabilities, 2006
Recently, more attention is being given to identifying aging-related and dementia-related pathological changes in performance and cognition among persons with intellectual disabilities (ID). This literature review examines age-related differences in specific aspects of cognitive functioning and cognitive performance of people with ID and…
Descriptors: Mental Retardation, Alzheimers Disease, Dementia, At Risk Persons
Maatta, Tuomo; Tervo-Maatta, Tuula; Taanila, Anja; Kaski, Markus; Iivanainen, Matti – Down Syndrome Research and Practice, 2006
The mental health, adaptive behaviour and intellectual abilities of people with Down syndrome (n=129) were evaluated in a population-based survey of social and health care records. Females had better cognitive abilities and speech production compared with males. Males had more behavioural problems than females. Behaviour suggestive of attention…
Descriptors: Speech Communication, Behavior Problems, Attention Deficit Hyperactivity Disorder, Age Differences
