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Direct linkSandra V. Loosli; Lennart C. Neumann; Elisabeth Wlasich; Catharina Prix; Laura Koll; Endy Weidinger; Jonathan Vöglein; Olivia Wagemann; Adrian Danek; Georg Nübling; Johannes Levin – Journal of Intellectual & Developmental Disability, 2024
Background: The CAMDEX-DS is an instrument to diagnose Alzheimer's disease (AD) in Down syndrome consisting of an informant interview and a cognitive test battery (CAMCOG-DS). Measurement properties of the German CAMDEX-DS were investigated. Method: Fifty-five adults with Down syndrome (19-58 years) participated in this observational study.…
Descriptors: Foreign Countries, Diagnostic Tests, Alzheimers Disease, Down Syndrome
Brianna Piro-Gambetti; Emily K. Schworer; Benjamin Handen; Masha Glukhovskaya; Sigan L. Hartley – Journal of Intellectual Disabilities, 2024
Adults with Down syndrome (DS) experience high risk for Alzheimer's disease (AD), but there is variability in the timing of transition from a cognitively stable state to prodromal AD and dementia. The present study examined the association between a modifiable lifestyle factor, employment complexity, and cognitive decline across two time points in…
Descriptors: Employment, At Risk Persons, Alzheimers Disease, Vocational Education
Handen, Benjamin L. – American Journal on Intellectual and Developmental Disabilities, 2020
Adults with Down syndrome are at high risk for Alzheimer's disease (AD), with most individuals developing clinical dementia by their late 60s. This increased risk for AD has been attributed, at least in part, to triplication and overexpression of the gene for amyloid precursor protein (APP) on chromosome 21, leading to elevated levels of amyloid…
Descriptors: Adults, Down Syndrome, Alzheimers Disease, At Risk Persons
Smith, Elizabeth; Hedge, Craig; Jarrold, Christopher – American Journal on Intellectual and Developmental Disabilities, 2019
Executive function (EF) decline is a consistent early sign of Alzheimer's disease (AD) among adults with Down syndrome (DS), which means that baseline measures of EF for individuals with DS are vital to allow detection of meaningful decline. We developed a framework to extract measures of three core components of EF (memory updating, inhibitory,…
Descriptors: Executive Function, Down Syndrome, Identification, Clinical Diagnosis
Download full textClarke-Vivier, Sara; Lyford, Corie; Thomson, Lynn – LEARNing Landscapes, 2017
Through the perspectives of a museum educator, an art educator, and an educational researcher, this article explores the evolution of shared definitions of "well-being" in the development of a museum- and arts-based program for adults with Alzheimer's disease and related dementias (ADRD). By piecing together the authors' first-person…
Descriptors: Alzheimers Disease, Dementia, Art Education, Art Activities
Kenshole, Athena V.; Gallichan, Deanna; Pahl, Sabine; Clibbens, John – Journal of Applied Research in Intellectual Disabilities, 2017
Background: Lifestyle has previously been associated with the onset of Alzheimer's disease (AD) in the typically developing population, but research investigating this association in Down syndrome (DS) is limited. Method: Adults with DS and AD (n = 27) were compared to adults with DS without AD (n = 30) on physical activity, diet, weight, where…
Descriptors: Alzheimers Disease, Life Style, Down Syndrome, Adults
