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Zigman, Warren B.; Lott, Ira T. – Mental Retardation and Developmental Disabilities Research Reviews, 2007
Down syndrome (DS) is characterized by increased mortality rates, both during early and later stages of life, and age-specific mortality risk remains higher in adults with DS compared with the overall population of people with mental retardation and with typically developing populations. Causes of increased mortality rates early in life are…
Descriptors: Heart Disorders, Alzheimers Disease, Mortality Rate, Down Syndrome

Kapell, Deborah; Nightingale, Beryle; Rodriguez, Ana; Lee, Joseph H.; Zigman, Warren B.; Schupf, Nicole – Mental Retardation, 1998
A study interviewed caregivers and reviewed medical records of 278 adults with mental retardation with and without Down syndrome. The adults with mental retardation had age-related disorders comparable to those in the general population, but there was an increased frequency of thyroid disorders, nonischemic heart disorders, and sensory impairment.…
Descriptors: Adults, Downs Syndrome, Heart Disorders, Incidence