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Zigman, Warren B.; Lott, Ira T. – Mental Retardation and Developmental Disabilities Research Reviews, 2007
Down syndrome (DS) is characterized by increased mortality rates, both during early and later stages of life, and age-specific mortality risk remains higher in adults with DS compared with the overall population of people with mental retardation and with typically developing populations. Causes of increased mortality rates early in life are…
Descriptors: Heart Disorders, Alzheimers Disease, Mortality Rate, Down Syndrome
Zigman, Warren B.; And Others – American Journal on Mental Retardation, 1996
Comparison of adults with mental retardation either with or without Down syndrome and under or over 50 years of age found a significantly higher rate of dementia only in Down syndrome subjects over 50. However, the observed incidence based on functional findings was substantially below the presumed 100% prevalence of neuropathological markers of…
Descriptors: Adaptive Behavior (of Disabled), Adults, Alzheimers Disease, Daily Living Skills