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Crutel, Véronique; Lambert, Estelle; Penelaud, Pierre-François; Albarrán Severo, Cristina; Fuentes, Joaquin; Rosier, Antoine; Hervás, Amaia; Marret, Stéphane; Oliveira, Guiomar; Parellada, Mara; Kyaga, Simon; Gouttefangeas, Sylvie; Bertrand, Marianne; Ravel, Denis; Falissard, Bruno – Journal of Autism and Developmental Disorders, 2021
There are currently no approved pharmacological treatments to improve social reciprocity and limit repetitive and rigid behaviors in autism spectrum disorder (ASD). We describe the design of two Phase III studies evaluating the efficacy/safety of bumetanide oral liquid formulation in ASD. These are international, multicenter, randomized,…
Descriptors: Autism, Pervasive Developmental Disorders, Children, Adolescents