Large numbers of qualified students do not apply to and enroll in college. Yet, earning a college degree is one of the primary pathways for economic success and is increasingly required for good jobs and high wages. A number of programs and practices aim to improve college readiness and enrollment, including "Take Stock in Children's® (TSIC's®) Facilitating Long-term Improvements in Graduation" and "Higher Education for Tomorrow" ("FLIGHT") program. "FLIGHT" provides mentoring, scholarships, and additional support services to help disadvantaged middle and high school students stay on track for graduation, apply to college, and enroll in college. "FLIGHT" students also have access to college transition and retention services in their first three semesters of college. This What Works Clearinghouse (WWC) report, part of the WWC's Transition to College topic area, explores the effects of the "FLIGHT" program on student success. The WWC identified six studies of "FLIGHT", and one study met WWC standards. [For the Intervention Snapshot, see ED594578. For the Intervention Brief, see ED594577.]