Talent Development Middle Grades Program (TDMG) is a whole school reform approach for large middle schools that face serious problems with student attendance, discipline, and academic achievement. The program includes both structural and curriculum reforms. The What Works Clearinghouse (WWC) identified 17 studies of TDMG that were published or released between 1988 and 2008. Fourteen studies are out of the scope of the review, as defined by the Dropout Prevention protocol. Two of these studies do not present primary research, and 12 do not examine outcomes within a domain specified in the protocol. Three studies of the TDMG fall within the scope of the Dropout Prevention review protocol, but do not meet WWC evidence standards. The lack of studies meeting WWC evidence standards means that, at this time, the WWC is unable to draw any conclusions based on research about the effectiveness or ineffectiveness of TDMG.