Project-based learning (PBL) takes student engagement to a higher level through reflective collaboration, inquiry, critical thinking, problem solving, and personal relevance. This article explains how six high school teachers developed an interconnected, interdisciplinary STEM-focused PBL called "Sculpting the Barnyard Gene Pool." The objective was to engage students in an authentic learning experience by immersing them in the biological and engineering worlds of chicken genetics, chicken hatcheries, and livestock industry involvement.