Instructional inquiry models are curricular and instructional practices that can promote, facilitate, and engage students in scientific inquiry and science content. However, current, existing learning-cycle models do not specifically incorporate essential instructional teaching strategies that promote or document strong conceptual understanding and process-skill development for all students. In this article, the authors provide an approach that integrates the Know-Learn-Evidence-Wonder (KLEW) instructional teaching strategy within the 7E (Engage, Elicit, Explore, Explain, Elaborate, Evaluate, Extend) learning-cycle model to help teachers immerse students in a range of inquiry-based science experiences, particularly open inquiry, and demonstrate evidence of student reflection, learning, and understanding of a science topic. (Contains 1 figure and 1 online resource.)