In eighteen chronic schizophrenics, subcutaneous doses of the dopamine reception agonist, apomorphine, improved psychotic symptoms. The results are interpreted as a consequence of presynaptic dopamine receptor activationby apomorphine with a subsequent decrease in dopamine-mediated neural transmission. (Author/BB)

Examines in retrospect how federal support through different agencies has influenced scientific research on university campuses. As funding becomes more of a problem for universities, research funds should be used to solve local and national problems. (PS)

Presents results of a national commission's investigation of psychosurgery. Results indicate the procedure to be effective in the cure of patients suffering from pain accompanied by depression, while avoiding the destruction caused by prefrontal lobotomies. (SL)

Proposes the development of state-specific sciences" to overcome the problems of scientifically studying altered states of consciousness induced by drugs or meditation from the paradigm of the ordinary consciousness state. The requirements of good observation, public nature of the observation, logical theorizing, and testing of theories by…

The main focus of YpsychologicalI research ought always to be the discovery of simple laws; these may or may not lead to new measures." Discusses types of psychological laws, psychological measurement, and experimental designs to test qualitative laws. (Author/AL)

Discusses the increasing trend toward the pork-barrel funding of science projects, particularly for grants to academic institutions. Addresses the new strategies being employed by opponents of such funding. Describes some of the possible ramifications of the various strategies and the perceived link between science funding and economic growth. (TW)

Reports that amphetamine given to normal boys resulted in a marked decrease in motor activity and reaction time, and improved performance on cognitive test, a response similar to those observed in hyperactive children. (SL)

Reports bita-Adrenergic antagonists injected into rats trained in a passive avoidance task produced time-dependent and dose-dependent decreases in retention of the task. Results were stereospecific and reversed by norepinephrine. (SL)

Encourages holistic viewpoint in scientific research, particularly in the integration of isolated, short-range projects into ecosystems studies. Discusses links of the ecosystem level of research with the social sciences, assessment of technological and environmental impact, establishment of economic values, and political thought. (CS)

Discusses the National Research Act (H.R. 7724). Provisions of the act, such as the banning of fetal research, circumscribe the freedom of scientists to manage their professional lives as they alone see fit. (PEB)

Describes the main features of the legislation establishing the National Institute of Education, and speculates on the likely impact on education of the research and development activities initiated and supported by the Institute when funded. (AL)

This Nobel lecture describes the development and role of maximum principles in economic research as practiced by the author. (AL)

Reviews the proposed 1979 federal budget for basic research for the National Institutes of Health (NIH), National Science Foundation (NSF), National Aeronautics and Space Administration (NASA), Environmental Protection Agency (EPA), Department of Defense, and Department of Energy. (SL)

Reports that a number of minor physical anomalies, assessable soon after birth, are significantly related to a cluster of behaviors at age three that are frequently labeled hyperactivity. (SL)

Discusses social, political, and ethical aspects of conducting medical clinical trials as well as their cost, benefits, and pitfalls. (SL)