In eighteen chronic schizophrenics, subcutaneous doses of the dopamine reception agonist, apomorphine, improved psychotic symptoms. The results are interpreted as a consequence of presynaptic dopamine receptor activationby apomorphine with a subsequent decrease in dopamine-mediated neural transmission. (Author/BB)

It has recently been shown that perceived motion, in the absence of any appropriate retinal motion, is a sufficient stimulus to generate smooth pursuit eye motions. However, three experiments show that perceived motion is not necessary for pursuit, but that retinal motion always governs pursuit. (BB)

The Gordon Research Conferences were established to stimulate research in universities, research foundations, and industrial laboratories. The topics for the conferences are listed as well as the locations and scheduled presentations at each conference. (CS)

Electroencephalograms were analyzed during performance of verbal and spatial tasks. Complex scalp distributions of theta-, beta-, and, to a lesser extent, alpha-band spectral intensities discriminated between the two members of a pair of tasks, such as writing sentences and Koh's block design. (Author/BB)

A new method generates specific predictions concerning the expected frequencies of aphasia after unilateral injury to the brain in the left- and right-handed. These predictions are then compared with the observed data for all known studies between 1935 and 1973 to derive the best-fitting model of hemispheric speech lateralization in the left- and…

Reviews three years of research on the effects of marihuana in man. Previously known clinical mental and physical effects have been confirmed. Causes and mechanisms of these effects generally remain undetermined in man and animals. Social implications and long term effects require additional study, although usage appears detrimental. (JM)

Describes research on synergistic effects of alcohol and other drugs, particularly barbiturates. Proposes biochemical mechanisms to explain alcoholics' tolerance of other drugs when sober, and increased sensitivity when drunk. (AL)

New systems for analyzing large numbers of body fluid components can be used in the clinical laboratory. (Author/RH)

Describes three methods and their advantages and disadvantages for introducing genes into animals. Discusses the predictability and tissue-specificity of the injected genes. Outlines the applications of transgenic technology for studying gene expression, the early stages of mammalian development, mutations, and the molecular nature of chromosomes.…

Proposes a hypothesis suggesting that parts of the central nervous system that contain norepinephrine and dopamine are dynamically interrelated under stressful conditions in a compensatory way. (MLH)

Discussed is the discovery which may help to explain epidermal growth factor effects on the cell skeleton. The role of a protein called profilin in the regulation of the microfilament system is described. (CW)

Presents a hypothesis about the biochemical processes involved in memory storage. The postulated mechanism is initiated by a signal that is unusual but not unlikely to occur and produces an irreversible change in a key component of synaptic chemistry. Other features of the mechanism and experiments supporting the hypothesis are considered. (JN)

Reviews the features of two classes of learning theories. Reports evidence supporting a statistical configuration" theory, suggesting that temporal patterns of neurophysiological waves in the average activity of extensive anatomical brain regions may constitute the basis of subjective experience. (AL)

Rod-isolation techniques show that light-adapted human rods detect flicker frequencies as high as 28 hertz, and that the function relating rod critical flicker frequency to stimulus intensity contains two distinct branches. (MLH)

Advances in the genetics and cell biology of muscle development are discussed. In-vitro analysis of the renaturation, polymerization, and three-dimensional structure of the purified proteins involved is described. (CW)