This project looks to fill a critical gap in our knowledge of the emergence of new forms of power, knowledge, and subjectivation that emerged during the industrial period in the United States and that continue to operate today. This critical hole is the role of what we will term "numerical mediation," which is the means by which the…

Information retrieval techniques have been applied to biomedical research for a variety of purposes, such as textual document retrieval and molecular data retrieval. As biomedical research evolves over time, information retrieval is also constantly facing new challenges, including the growing number of available data, the emerging new data types,…

When a new student comes to play an educational game, how can we determine what content to give them such that they learn as much as possible? When a frustrated customer calls in to a helpline, how can we determine what to say to best assist them? When an ill patient comes in to the clinic, how do we determine what tests to run and treatments to…

The development in information science has enabled an explosive growth of data, which attracts more and more researchers to engage in the field of big data analytics. Noticeably, in many real-world applications, large amounts of data are imbalanced data since the events of interests occur infrequently. Classification of imbalanced data is an…

Numerous organizations collect and distribute non-aggregate personal data for a variety of different purposes, including demographic and public health research. In these situations, the data distributor is responsible with the protection of the anonymity and personal information of individuals. Microaggregation is one of the most commonly used…

Interdisciplinary research in computer science requires the development of computational techniques for practical application in different domains. This usually requires careful integration of different areas of technical expertise. This dissertation presents image and time series analysis algorithms, with practical interdisciplinary applications…

In my dissertation, I will present my research which contributes to solve the following three open problems from biomedical informatics: (1) Multi-task approaches for microarray classification; (2) Multi-label classification of gene and protein prediction from multi-source biological data; (3) Spatial scan for movement data. In microarray…

Compressed sensing (CS) is an emerging signal acquisition framework that goes against the traditional Nyquist sampling paradigm. CS demonstrates that a sparse, or compressible, signal can be acquired using a low rate acquisition process. Since noise is always present in practical data acquisition systems, sensing and reconstruction methods are…

Graphs are widely used to model structures and relationships of objects in various scientific and commercial fields. Chemical molecules, proteins, malware system-call dependencies and three-dimensional mechanical parts are all modeled as graphs. In this dissertation, we propose to mine and index those graph data to enable fast and scalable search.…

1.2 billion users in Facebook, 17 million articles in Wikipedia, and 190 million tweets per day have demanded significant increase of information processing through Internet in recent years. Similarly life sciences and bioinformatics also have faced issues of processing Big data due to the explosion of publicly available genomic information…

In the modern world information has become the new power. An increasing amount of efforts are being made to gather data, resources being allocated, time being invested and tools being developed. Data collection is no longer a myth; however, it remains a great challenge to create value out of the enormous data that is being collected. Data modeling…

Structural health monitoring (SHM) has gained significant popularity in the last decade. This growing interest, coupled with new sensing technologies, has resulted in an overwhelming amount of data in need of management and useful interpretation. Acoustic emission (AE) testing has been particularly fraught by the problem of growing data and is…

Clustering is one of the most common data mining tasks, used frequently for data organization and analysis in various application domains. Traditional machine learning approaches to clustering are fully automated and unsupervised where class labels are unknown a priori. In real application domains, however, some "weak" form of side…

Fifty percent of college-bound students graduate from high school underprepared for mathematics at the post-secondary level. As a result, thirty-five percent of college students take developmental mathematics courses. What is even more shocking is the high failure rate (ranging from 35 to 42 percent) of students enrolled in developmental…