The problem addressed through this study was the absence of a critical examination of laboratory exercises used with first-year nonbiology majors and the deployment of virtual laboratories in the biology department at the project site university without critical analyses associated with the efficacy of virtual labs. Grounded in Mayer's cognitive…

Ubiquitin is essential for eukaryotic life and varies in only 3 amino acid positions between yeast and humans. However, recent deep sequencing studies indicate that ubiquitin is highly tolerant to single mutations. We hypothesized that this tolerance would be reduced by chemically induced physiologic perturbations. To test this hypothesis, a class…

Undergraduate physics laboratory curriculum has undergone significant modification in recent decades in response to research and recommendations from educational and professional organizations and stakeholders. These reforms address multiple issues, such as 1) lack of student agency in experimentation, 2) an incomplete framework for student…

A study was conducted to investigate the extent to which previous science achievement affected student performance in traditional hands-on and virtual laboratory environments. A sample of 70 first-year college students was employed in a counterbalanced A-B-A-B experimental design. The study spanned four instructional weeks of laboratory…

Students' learning in inquiry-based investigations has drawn considerable attention of the science education community. Inquiry activities can be viewed as knowledge construction processes in which students are expected to develop conceptual understanding and critical thinking abilities. Our study aimed to explore the effect of experiments…

"Visualization" of chemical phenomena often has been limited in the teaching laboratories to the sense of sight. We have developed chemistry experiments that rely on senses other than eyesight to investigate chemical concepts, make quantitative determinations, and familiarize students with chemical techniques traditionally designed using only…

Chapter 1: The role of cell division in protein expression is important to understand in order to guide the development of better nonviral gene delivery materials that can transport DNA to the nucleus with high efficiency for a variety of cell types, particularly when nondividing cells are targets of gene therapy. We evaluated the relationship…

In the U.S., future economic viability is being challenged by an increasing inability to replace retiring engineers and scientists through the year 2020 due to declines in learner motivation and proficiency in science. The expository laboratory appears to be linked with non-engagement and is one possible contributing factor to this problem…

This dissertation has two primary concerns: (i) evaluating the uncertainty and prediction capabilities of a nanodiamond drug delivery model using Bayesian calibration and bias correction, and (ii) determining conceptual difficulties of multi-scale analysis from an engineering education perspective. A Bayesian uncertainty quantification scheme…