Leaders in higher education face increasing pressure to ensure their institutions are well-positioned to adapt to our changing world. As part of responding to these demands, a growing number of institutions have established dedicated teams of in-house experts to support this work and the culture change around it, broadly termed academic change or academic innovation. This report details methods and findings of a comprehensive survey of academic innovation department leaders in colleges and universities across the United States. The survey received responses from 138 academic innovation leaders who shared details on the scope of their work, the structures and institutional resources supporting it, their impact, and their perspectives on contemporary challenges including the COVID-19 pandemic and its influence on postsecondary learning. Ten years after the first such survey, findings included evidence of increasing staffing and budgets, evolving priorities, shifting reporting structures, and technological advancement. Implications include expanding research and professional communities for this relatively new functional area within US higher education, recommendations for institutional leaders, and a focus on supporting continued growth. As a result, the report serves as a census of academic innovation units in an array of US colleges and universities, with details relevant for benchmarking and further research. The following are appended: (1) Data tables for all survey items; (2) Participating institution list; and (3) Survey instrument. [This report was produced by the University of Michigan, Center for Academic Innovation and Quantum Thinking. Additional sponsors for this report include: Class Technologies, Acadeum, Intelliboard, Auburn University, Biggio Center for the Enhancement of Teaching and Learning Leading Academic Change, EdPlus at Arizona State University, Bentley University, University System of Maryland, William E. Kirwan Center for Academic Innovation, POD Network in Higher education (POD), and SAB Creative & Consulting.]